Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135456 | 1.00 | ALDH1A1 (0.48) | ALDH1A1HTTHPGDNPSR1HSP90AA1 | |
| SCHEMBL21135497 | 1.00 | ALDH1A1 (0.48) | ALDH1A1HTTHPGDNPSR1HSP90AA1 | |
| SCHEMBL1994967 | 0.92 | HTT (0.50) | ALDH1A1HTTHPGDNPSR1HSP90AA1 | |
| SCHEMBL7470844 | 0.85 | ALDH1A1 (0.50) | ALDH1A1HTTHPGDNPSR1HSP90AA1 | |
| SCHEMBL8207095 | 0.84 | HTT (0.52) | ALDH1A1HTTHPGDNPSR1HSP90AA1 | |
| SCHEMBL7051582 | 0.84 | DPP4 (0.56) | ALDH1A1HTTHPGDNPSR1HSP90AA1 | |
| SCHEMBL7468160 | 0.84 | DPP4 (0.56) | ALDH1A1HTTHPGDNPSR1HSP90AA1 | |
| SCHEMBL27976340 | 0.83 | NPC1 (0.51) | ALDH1A1HPGDNPSR1NPC1RAB9A | |
| SCHEMBL1663461 | 0.81 | USP2 (0.51) | ALDH1A1HPGDMEN1KMT2ANPC1 | |
| SCHEMBL3898465 | 0.81 | HPGD (0.61) | ALDH1A1HTTHPGDNPSR1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329307-B2 | Heterocyclic compounds as inhibitors of platelet aggregation | UNIVERSITE DE MONTREAL (CA) | 2019-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329307-B2 | Heterocyclic compounds as inhibitors of platelet aggregation | F12, F2, F3 | ALDH1A1 1559/4885HTT 2643/4885HPGD 740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.