Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28339053 | 0.83 | ALDH1A1 (0.56) | MEN1ALDH1A1MAPTKMT2ACTSK | |
| SCHEMBL30987733 | 0.81 | CHRM2 (0.40) | MEN1ALDH1A1MAPTKMT2ACTSK | |
| SCHEMBL2737899 | 0.80 | MEN1 (0.51) | MEN1ALDH1A1MAPTKMT2ACTSK | |
| SCHEMBL15828463 | 0.78 | MEN1 (0.61) | MEN1ALDH1A1MAPTKMT2ACTSK | |
| SCHEMBL18039833 | 0.78 | MEN1 (0.61) | MEN1ALDH1A1MAPTKMT2ACTSK | |
| SCHEMBL627415 | 0.77 | HSD17B10 (0.47) | CHRM2CHRM1CHRM3HSD17B10GPR119 | |
| SCHEMBL6078598 | 0.77 | HSD17B10 (0.47) | CHRM2CHRM1CHRM3HSD17B10GPR119 | |
| Ethane SCHEMBL4767713 | 0.77 | HSD17B10 (0.47) | CHRM2CHRM1CHRM3HSD17B10GPR119 | |
| SCHEMBL883031 | 0.77 | HSD17B10 (0.47) | CHRM2CHRM1CHRM3HSD17B10GPR119 | |
| SCHEMBL12369398 | 0.77 | CHRM2 (0.44) | CHRM2CHRM1CHRM3HSD17B10GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019112457-A1 | DOPAMINE-Β-HYDROXYLASE INHIBITORS | BIAL - PORTELA & Cª, S.A. (PT) | 2019-06-13 | — | — | WO | disclosed |