Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 17/20 | 0.51 |
| ▸ | PIK3R1 | P27986 | 8/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.51 |
| ▸ | MTOR | P42345 | 4/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135850 | 0.89 | PIK3CA (0.54) | PIK3CAPIK3R1PIK3CDMTORKDM4E | |
| SCHEMBL21135849 | 0.88 | PIK3CA (0.42) | PIK3CAPIK3R1PIK3CDMTORSMN1; SMN2 | |
| SCHEMBL21135851 | 0.87 | PIK3CA (0.42) | PIK3CAPIK3R1PIK3CDMTORPIK3CB | |
| SCHEMBL21135852 | 0.84 | PIK3CA (0.39) | PIK3CAPIK3R1PIK3CDMTOR | |
| SCHEMBL23272149 | 0.83 | KDM4E (0.53) | PIK3CAPIK3R1PIK3CDALDH1A1KDM4E | |
| SCHEMBL30312327 | 0.83 | KDM4E (0.53) | PIK3CAPIK3R1PIK3CDALDH1A1KDM4E | |
| SCHEMBL30366721 | 0.79 | PIK3CA (0.56) | PIK3CAPIK3R1PIK3CDMTORPIK3CB | |
| SCHEMBL21135207 | 0.76 | ATR (0.41) | PIK3CAPIK3R1PIK3CDPIK3CBALDH1A1 | |
| SCHEMBL21054567 | 0.75 | KDM4E (0.54) | PIK3CAPIK3R1PIK3CDALDH1A1KDM4E | |
| SCHEMBL30312448 | 0.75 | KDM4E (0.54) | PIK3CAPIK3R1PIK3CDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |