Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.47 |
| ▸ | MTOR | P42345 | 6/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135294 | 0.91 | MAPT (0.44) | STAT3PIK3CAMTORPIK3CD | |
| SCHEMBL21135209 | 0.90 | CHEK1 (0.52) | STAT3PIK3CAMTORCHEK1PIK3CD | |
| SCHEMBL21135404 | 0.82 | PIK3R1 (0.51) | STAT3PIK3CAMTORPIK3R1KDM4E | |
| SCHEMBL30312468 | 0.79 | PIKFYVE (0.60) | STAT3PIK3CAMTORCHEK1PIK3CD | |
| SCHEMBL21053866 | 0.79 | PIKFYVE (0.60) | STAT3PIK3CAMTORCHEK1PIK3CD | |
| SCHEMBL21135489 | 0.79 | PIK3CD (0.64) | STAT3PIK3R1PIK3CD | |
| SCHEMBL21135197 | 0.78 | PIK3CD (0.52) | PIK3R1PIK3CD | |
| SCHEMBL21135863 | 0.77 | PIK3CD (0.51) | PIK3R1PIK3CD | |
| SCHEMBL21135293 | 0.74 | MAPT (0.46) | STAT3PIK3CAMTORPIK3R1PIK3CD | |
| SCHEMBL30312519 | 0.73 | PIKFYVE (0.68) | PIK3CAMTORCHEK1PIK3CDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |