SCHEMBL21136026

SCHEMBL21136026

COC(=O)CC(F)(C1CCCCC1)S(=O)(=O)O

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 4/20 0.40
GLA P06280 1/20 0.34
NPSR1 Q6W5P4 2/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
SSTR4 P31391 1/20 0.31
PDK1 Q15118 1/20 0.31
PDK2 Q15119 1/20 0.31
PDK3 Q15120 1/20 0.31
PDK4 Q16654 1/20 0.31
TSHR P16473 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
GAA P10253 1/20 0.31
ALDH1A1 P00352 2/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
ATM Q13315 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21136023 0.82 MEN1 (0.33) NPSR1MEN1KMT2APDK1PDK2
SCHEMBL21135961 0.76 TSHR (0.32) TSHRL3MBTL1GAA
SCHEMBL21135999 0.76
SCHEMBL21135696 0.76 EPHX2 (0.32) EPHX2NPSR1
SCHEMBL21136394 0.76 EPHX2 (0.38) EPHX2GLANPSR1MEN1KMT2A
SCHEMBL21136607 0.74 EPHX2 (0.36) EPHX2GLATSHRL3MBTL1ALDH1A1
SCHEMBL21136583 0.74 EPHX1 (0.39) EPHX2GLA
SCHEMBL21136019 0.73 CHRM2 (0.34) TSHRL3MBTL1GAA
SCHEMBL21136015 0.71 GRM2 (0.32)
SCHEMBL21135763 0.71 NR1H2 (0.33) EPHX2NPSR1PDK1PDK2PDK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190196326-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, AND METHOD OF MANUFACTURING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2019-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190196326-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, AND METHOD OF MANUFACTURING ELECTRONIC DEVICE RER1, ACTR5, RAD51 EPHX2 252/4885GLA 392/4885NPSR1 2278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.