⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22757768 | 0.74 | ALDH1A1 (0.32) | — | |
| SCHEMBL21101297 | 0.67 | — | — | |
| SCHEMBL14413841 | 0.67 | — | — | |
| SCHEMBL21136844 | 0.65 | — | — | |
| SCHEMBL18063418 | 0.63 | — | — | |
| SCHEMBL21911281 | 0.62 | — | — | |
| SCHEMBL21276797 | 0.60 | POLB (0.30) | — | |
| SCHEMBL21136359 | 0.59 | — | — | |
| SCHEMBL21910797 | 0.59 | — | — | |
| SCHEMBL11692854 | 0.59 | SMN1; SMN2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140647-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2022-06-30 | — | — | WO | disclosed |
| WO-2020247444-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC, (US) | 2020-12-10 | — | — | WO | disclosed |
| WO-2019113173-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-06-13 | — | — | WO | disclosed |