Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3934422 | 0.86 | PNMT (0.38) | TAAR1KDM4E | |
| SCHEMBL20252575 | 0.84 | TAAR1 (0.43) | TAAR1AOC3MAOBCD274KDM4E | |
| SCHEMBL8163553 | 0.84 | TAAR1 (0.39) | TAAR1AOC3KDM4EIDO1MEN1 | |
| SCHEMBL27660692 | 0.84 | TAAR1 (0.39) | TAAR1AOC3KDM4EIDO1MEN1 | |
| Hydrochloric Acid SCHEMBL10351316 | 0.84 | PNMT (0.37) | TAAR1KDM4E | |
| SCHEMBL3672443 | 0.81 | TAAR1 (0.48) | TAAR1AOC3MAOBMPOSLC6A4 | |
| SCHEMBL21456029 | 0.78 | PNMT (0.40) | TAAR1AOC3MAOB | |
| SCHEMBL8074849 | 0.78 | PNMT (0.40) | TAAR1KDM4E | |
| SCHEMBL31737937 | 0.77 | TAAR1 (0.44) | TAAR1KDM4E | |
| SCHEMBL170879 | 0.77 | TAAR1 (0.45) | TAAR1KDM4EMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019112968-A1 | PROCESSES TO PRODUCE ELAGOLIX | WANG PENG (US) | 2019-06-13 | — | — | WO | disclosed |