Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 5/20 | 0.72 |
| ▸ | CDK2 | P24941 | 5/20 | 0.72 |
| ▸ | CDK1 | P06493 | 4/20 | 0.72 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.72 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.48 |
| ▸ | AHCY | P23526 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.42 |
| ▸ | PI4KA | P42356 | 2/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24709725 | 0.85 | CCNE1 (0.72) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL27516653 | 0.84 | CCNE1 (0.70) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL8767031 | 0.84 | CCNE1 (1.00) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL22300666 | 0.84 | CCNE1 (0.70) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL23619320 | 0.82 | CDK1 (0.60) | CCNE1CDK2CDK1CCNB1ADORA2A | |
| SCHEMBL4022228 | 0.82 | CCNE1 (0.68) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL5023964 | 0.81 | CCNE1 (0.66) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL1377647 | 0.81 | CDK1 (0.76) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL4022224 | 0.81 | CCNE1 (0.66) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL986731 | 0.81 | CDK1 (0.66) | CCNE1CDK2CDK1CCNB1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240066047-A1 | ANTIBODY-DRUG CONJUGATES COMPRISING A CYCLIC DINUCLEOTIDE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-02-29 | — | — | US | disclosed |
| US-20210137962-A9 | CYCLIC DINUCLEOTIDE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-05-13 | — | — | US | disclosed |
| US-10980825-B2 | Cyclic dinucleotide | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-04-20 | — | — | US | disclosed |
| US-20190192549-A1 | CYCLIC DINUCLEOTIDE | TAKEDA PHARMACEUTICALS CO (JP) | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240066047-A1 | ANTIBODY-DRUG CONJUGATES COMPRISING A CYCLIC DINUCLEOTIDE | STING1, TLR9, CGAS | CCNE1 4880/4885CDK2 4868/4885CDK1 4739/4885 |
| US-20210137962-A9 | CYCLIC DINUCLEOTIDE | STING1, CGAS, MAVS | CCNE1 4831/4885CDK2 4730/4885CDK1 4501/4885 |
| US-10980825-B2 | Cyclic dinucleotide | STING1, CGAS, MAVS | CCNE1 4831/4885CDK2 4730/4885CDK1 4501/4885 |
| US-20190192549-A1 | CYCLIC DINUCLEOTIDE | STING1, CGAS, MAVS | CCNE1 4831/4885CDK2 4730/4885CDK1 4501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.