Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | PARL | Q9H300 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94530 | 0.91 | HTR6 (0.50) | PSIP1TDP1ALDH1A1HSD17B10HTR6 | |
| SCHEMBL29067362 | 0.89 | HTR6 (0.48) | PSIP1TDP1ALDH1A1HSD17B10HTR6 | |
| Water SCHEMBL28395492 | 0.89 | HTR6 (0.48) | PSIP1TDP1ALDH1A1HSD17B10HTR6 | |
| SCHEMBL28888539 | 0.89 | HTR6 (0.48) | PSIP1TDP1ALDH1A1HSD17B10HTR6 | |
| SCHEMBL614636 | 0.89 | HTR6 (0.48) | PSIP1TDP1ALDH1A1HSD17B10HTR6 | |
| SCHEMBL417960 | 0.89 | HTR6 (0.48) | PSIP1TDP1ALDH1A1HSD17B10HTR6 | |
| SCHEMBL10400632 | 0.89 | HTR6 (0.48) | PSIP1TDP1ALDH1A1HSD17B10HTR6 | |
| Ammonia Solution, Strong SCHEMBL8436849 | 0.89 | HTR6 (0.48) | PSIP1TDP1ALDH1A1HSD17B10HTR6 | |
| SCHEMBL31149858 | 0.89 | HTR6 (0.48) | PSIP1TDP1ALDH1A1HSD17B10HTR6 | |
| SCHEMBL28596320 | 0.89 | HTR6 (0.48) | PSIP1TDP1ALDH1A1HSD17B10HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556978-A | PREPARING 1R-CIS, 1'R-CIS 2',2'-/3,11-DIOXO-4,10-DIOXATRIDECYLENE/-BIS/1,2,3,4-TETRA-HY DRO-6,7-DIMETHOXY-2-METHYL-1-VERATRYLISOQUINOLINIUM SALT | GLAXO WELLCOME INC. (US) | 1996-09-17 | — | — | US | claimed |
| US-8158795-B2 | Process for the purification of neuromuscular blocking agents | FARMABIOS S.P.A. (IT) | 2012-04-17 | — | — | US | disclosed |
| US-20100016596-A1 | PROCESS FOR THE PURIFICATION OF NEUROMUSCULAR BLOCKING AGENTS | FARMABIOS S.P.A. (IT) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016596-A1 | PROCESS FOR THE PURIFICATION OF NEUROMUSCULAR BLOCKING AGENTS | GLRB, GRIN2C, CHRNA5 | PSIP1 3647/4885TDP1 4629/4885ALDH1A1 3724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.