Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.64 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.64 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2618715 | 0.83 | EHMT2 (0.77) | EHMT2EHMT1APOBEC3GALDH1A1NPC1 | |
| SCHEMBL11833495 | 0.83 | EHMT2 (0.70) | EHMT2EHMT1APOBEC3GALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL11726971 | 0.82 | EHMT2 (0.94) | EHMT2EHMT1APOBEC3GALDH1A1NPC1 | |
| SCHEMBL29349787 | 0.79 | EHMT2 (1.00) | EHMT2EHMT1APOBEC3GALDH1A1NPC1 | |
| SCHEMBL27972393 | 0.79 | EHMT2 (1.00) | EHMT2EHMT1APOBEC3GALDH1A1NPC1 | |
| SCHEMBL21174 | 0.79 | EHMT2 (1.00) | EHMT2EHMT1APOBEC3GALDH1A1NPC1 | |
| SCHEMBL19268265 | 0.79 | EHMT2 (0.64) | EHMT2EHMT1APOBEC3GALDH1A1NPC1 | |
| SCHEMBL327697 | 0.79 | EHMT2 (0.64) | EHMT2EHMT1APOBEC3GALDH1A1NPC1 | |
| SCHEMBL9846637 | 0.79 | EHMT2 (0.64) | EHMT2EHMT1APOBEC3GALDH1A1NPC1 | |
| SCHEMBL11822538 | 0.79 | EHMT2 (0.64) | EHMT2EHMT1APOBEC3GALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10786455-B2 | Lipid-derived neutral nanoparticles | TRANSLATE BIO, INC. (US) | 2020-09-29 | — | — | US | disclosed |
| US-20190192435-A1 | LIPID-DERIVED NEUTRAL NANOPARTICLES | TRANSLATE BIO, INC. | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10786455-B2 | Lipid-derived neutral nanoparticles | PHOSPHO1, LPAR6, PLIN3 | EHMT2 2833/4885EHMT1 3069/4885APOBEC3G 3513/4885 |
| US-20190192435-A1 | LIPID-DERIVED NEUTRAL NANOPARTICLES | PHOSPHO1, LPAR6, PLIN3 | EHMT2 2833/4885EHMT1 3069/4885APOBEC3G 3513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.