SCHEMBL327697

SCHEMBL327697

CCSSc1ccccn1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.64
EHMT1 Q9H9B1 1/20 0.64
APOBEC3G Q9HC16 1/20 0.64
LMNA P02545 1/20 0.44
FBP1 P09467 2/20 0.41
ALDH1A1 P00352 4/20 0.41
RAB9A P51151 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
NPC1 O15118 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
TXN P10599 1/20 0.40
HPGD P15428 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
TSHR P16473 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
NOS3 P29474 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL1286383 0.98 EHMT2 (0.61) EHMT2EHMT1APOBEC3GLMNAFBP1
SCHEMBL30195130 0.84 EHMT2 (0.59) EHMT2EHMT1APOBEC3GLMNAALDH1A1
SCHEMBL423720 0.84 EHMT2 (0.59) EHMT2EHMT1APOBEC3GLMNAALDH1A1
Acrylic Acid SCHEMBL29224774 0.84 EHMT2 (0.46) EHMT2EHMT1APOBEC3GLMNAALDH1A1
Methacrylic Acid SCHEMBL28950373 0.84 EHMT2 (0.46) EHMT2EHMT1APOBEC3GLMNAALDH1A1
Acrylamide SCHEMBL23804873 0.83 EHMT2 (0.44) EHMT2EHMT1APOBEC3GLMNAALDH1A1
SCHEMBL14157325 0.83 EHMT2 (0.44) EHMT2EHMT1APOBEC3GLMNAALDH1A1
SCHEMBL2618715 0.83 EHMT2 (0.77) EHMT2EHMT1APOBEC3GLMNAALDH1A1
SCHEMBL11833495 0.83 EHMT2 (0.70) EHMT2EHMT1APOBEC3GLMNAALDH1A1
SCHEMBL12107793 0.81 EHMT2 (0.55) EHMT2EHMT1APOBEC3GLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118330218-A Cathepsin B targeted activation type PET molecular probe and application thereof 江苏省原子医学研究所 2024-07-12 CN claimed
CN-113388003-B Aspartic acid proteolytic enzyme recognition reduction type molecular probe and application 江苏省原子医学研究所 2023-04-07 CN claimed
CN-113388003-A Aspartic acid proteolytic enzyme recognition reduction type molecular probe and application 江苏省原子医学研究所 2021-09-14 CN claimed
US-20250361260-A1 NUCLEOTIDE ANALOGUES SINGULAR GENOMICS SYSTEMS INC (US) 2025-11-27 US disclosed
US-20250339415-A1 DISULFIDE COMPOUNDS AS MEDICAMENTS CYTACOAT AB (SE) 2025-11-06 US disclosed
EP-4380567-B1 DISULFIDE COMPOUNDS AS MEDICAMENTS CYTACOAT AB (SE) 2025-05-07 EP disclosed
US-12215122-B2 Nucleotide analogues Singular Genomics Systems, Inc. (US) 2025-02-04 US disclosed
US-20240400602-A1 NUCLEOTIDE ANALOGUES FIRST-CITIZENS BANK & TRUST COMPANY 2024-12-05 US disclosed
US-12145960-B2 Nucleotide analogues Singular Genomics Systems, Inc. (US) 2024-11-19 US disclosed
US-20240316036-A1 DISULFIDE CONTAINING THERAPEUTICS AND DIAGNOSTICS FIRST-CITIZENS BANK & TRUST COMPANY 2024-09-26 US disclosed
US-20240269156-A1 DISULFIDE CONTAINING THERAPEUTICS FIRST-CITIZENS BANK & TRUST COMPANY 2024-08-15 US disclosed
US-20070087047-A1 Enhanced circulation effector composition and method ALZA CORPORATION 2007-04-19 US disclosed
US-7199223-B2 Water soluble polyoxyethylene glylcol polyvinylpyrrolidone, polyvinyl alcohol, polyoxazoline, and/or polyacryloylmorpholine, conjugated to antihemophilic factor NEKTAR THERAPEUTICS AL, CORPORATION (US) 2007-04-03 US disclosed
US-6251858-B1 DERIVATIVES OF GLYCOSYLAMINE IN WHICH THE OLIGOSIDES ARE FIXED ON AT LEAST ONE MOLECULE, MATRIX OR PARTICLE I.D.M. IMMUNO-DESIGNED MOLECULES (FR) 2001-06-26 US disclosed
EP-0766689-A1 NOVEL OLIGOSACCHARIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USES THEREOF I.D.M. IMMUNO-DESIGNED MOLECULES (FR) 1997-04-09 EP disclosed
WO-1996000229-A1 NOVEL OLIGOSACCHARIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USES THEREOF I.D.M. IMMUNO-DESIGNED MOLECULES (FR) 1996-01-04 WO disclosed
US-4237290-A ODORANTS, FLAVORINGS; REACTION OF A SULFONIUM SALT AND A MERCAPTAN GIVAUDAN CORPORATION (US) 1980-12-02 US disclosed
US-4188488-A ALKYLIMIDAZOLYL SUBSTITUENTS GIVAUDAN CORPORATION (US) 1980-02-12 US disclosed
US-4170594-A Oxazolyl-alkyl-disulphides as flavorants GIVAUDAN CORPORATION (US) 1979-10-09 US disclosed
US-4130562-A Odorant or flavoring thiazolyl disulphides GIVAUDAN CORPORATION (US) 1978-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12215122-B2 Nucleotide analogues NUDT1, POLN, TYMP EHMT2 2494/4885EHMT1 2450/4885APOBEC3G 226/4885
US-20240400602-A1 NUCLEOTIDE ANALOGUES ADAR, NUDT1, NSUN2 EHMT2 938/4885EHMT1 923/4885APOBEC3G 236/4885
US-20250339415-A1 DISULFIDE COMPOUNDS AS MEDICAMENTS SQOR, SFXN1, PDIA5 EHMT2 4300/4885EHMT1 3602/4885APOBEC3G 4248/4885
US-20240316036-A1 DISULFIDE CONTAINING THERAPEUTICS AND DIAGNOSTICS GPX1, GPX4, PDIA4 EHMT2 2946/4885EHMT1 3031/4885APOBEC3G 4047/4885
US-20250361260-A1 NUCLEOTIDE ANALOGUES ADAR, NUDT1, NSUN2 EHMT2 938/4885EHMT1 923/4885APOBEC3G 236/4885
US-20240269156-A1 DISULFIDE CONTAINING THERAPEUTICS P4HB, PDIA5, PDIA4 EHMT2 3151/4885EHMT1 3191/4885APOBEC3G 2768/4885
US-12145960-B2 Nucleotide analogues ITPA, POLB, NUDT1 EHMT2 2878/4885EHMT1 3389/4885APOBEC3G 437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.