SCHEMBL21137837

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22551275	0.81	MEN1 (0.42)	MEN1KMT2AALDH1A1KDM4E
	SCHEMBL22618744	0.80	PTPN1 (0.31)	MEN1KMT2AALDH1A1TDP1POLB
	SCHEMBL16896553	0.79	CYP1A2 (0.42)	CYP1A2NLRP3GABRA2GABRB2
	SCHEMBL23193188	0.79	PTPN1 (0.32)	—
	SCHEMBL14820135	0.78	CYP1A2 (0.49)	MEN1KMT2AALDH1A1TDP1POLB
	SCHEMBL16898794	0.77	CYP1A2 (0.45)	MEN1KMT2AALDH1A1POLBMAPT
	SCHEMBL2792417	0.77	ALDH1A1 (0.59)	KMT2AALDH1A1MAPTKDM4EHPGD
	SCHEMBL26315180	0.77	HDAC1 (0.61)	ALDH1A1MAPTKDM4EHPGDCYP1A2
	SCHEMBL3070077	0.76	PDE4B (0.53)	ALDH1A1CYP1A2
	SCHEMBL12571352	0.76	CDC7 (0.51)	ALDH1A1HPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.