Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 17/20 | 1.00 |
| ▸ | TDO2 | P48775 | 16/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22635723 | 0.96 | IDO1 (1.00) | IDO1TDO2CYP2C9CYP3A4ALDH1A1 | |
| SCHEMBL21138033 | 0.87 | IDO1 (1.00) | IDO1TDO2CYP2C9CYP3A4ALDH1A1 | |
| SCHEMBL21138036 | 0.85 | IDO1 (0.74) | IDO1TDO2CYP2C9CYP3A4 | |
| SCHEMBL21138029 | 0.85 | IDO1 (1.00) | IDO1TDO2CYP2C9CYP3A4 | |
| SCHEMBL21138038 | 0.83 | IDO1 (0.70) | IDO1TDO2CYP2C9CYP3A4 | |
| SCHEMBL22648325 | 0.82 | IDO1 (0.76) | IDO1TDO2CYP2C9CYP3A4RAB9A | |
| SCHEMBL21138148 | 0.80 | IDO1 (0.66) | IDO1TDO2CYP2C9CYP3A4ALDH1A1 | |
| SCHEMBL21061068 | 0.79 | IDO1 (0.66) | IDO1TDO2CYP2C9CYP3A4ALDH1A1 | |
| SCHEMBL22648520 | 0.79 | IDO1 (0.65) | IDO1TDO2CYP2C9CYP3A4ALDH1A1 | |
| SCHEMBL23271202 | 0.77 | IDO1 (1.00) | IDO1TDO2CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200352931-A1 | OXALAMIDES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | Phenex Discovery Verwaltungs-GmbH (DE) | 2020-11-12 | — | — | US | disclosed |
| WO-2019115586-A1 | OXALAMIDES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | Phenex Discovery Verwaltungs-GmbH (DE) | 2019-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200352931-A1 | OXALAMIDES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | IDO1, IDO2, INMT | IDO1 1/4885TDO2 7/4885CYP2C9 1667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.