Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
| ▸ | ITGAV | P06756 | 2/20 | 0.32 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | TOP1 | P11387 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23193057 | 0.94 | ELANE (0.35) | ELANEHDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL29293404 | 0.91 | ELANE (0.34) | ELANEHDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL31682827 | 0.91 | ELANE (0.36) | ELANEHDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL22618829 | 0.90 | ELANE (0.35) | ELANEHDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL23193189 | 0.90 | ELANE (0.34) | ELANEHDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL21137534 | 0.87 | HDAC6 (0.33) | ELANEHDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL21137596 | 0.87 | ELANE (0.34) | ELANEHDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL22618756 | 0.86 | ELANE (0.39) | ELANEHDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL21137619 | 0.86 | ELANE (0.39) | ELANEHDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL29293293 | 0.86 | ELANE (0.38) | ELANEHDAC6HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019114666-A1 | BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-06-20 | — | — | WO | disclosed |