Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.32 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29293404 | 0.97 | ELANE (0.34) | ELANEHDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL23193057 | 0.91 | ELANE (0.35) | ELANEHDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL21138197 | 0.90 | ELANE (0.37) | ELANEHDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL26784120 | 0.89 | ELANE (0.36) | ELANEHDAC6HDAC3HDAC1TOP1 | |
| SCHEMBL31682827 | 0.86 | ELANE (0.36) | ELANEHDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL21137534 | 0.86 | HDAC6 (0.33) | ELANEHDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL22618829 | 0.86 | ELANE (0.35) | ELANEHDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL22618756 | 0.84 | ELANE (0.39) | ELANEHDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL21137619 | 0.84 | ELANE (0.39) | ELANEHDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL29293467 | 0.84 | ELANE (0.36) | ELANEHDAC6HDAC3HDAC1TOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210101906-A2 | BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2021-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210101906-A2 | BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | DOCK11, PAICS, RHOA | ELANE 3216/4885HDAC6 384/4885HDAC8 282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.