Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21138202 | 0.78 | PDE8B (0.41) | — | |
| SCHEMBL21159423 | 0.77 | ABCB1 (0.33) | ABCB1HSP90AB1FBP1 | |
| SCHEMBL21057455 | 0.69 | KDM1A (0.40) | — | |
| SCHEMBL14619182 | 0.67 | CDK1 (0.60) | — | |
| SCHEMBL29386483 | 0.67 | CDK1 (0.60) | — | |
| SCHEMBL29388366 | 0.64 | CDK1 (0.67) | — | |
| SCHEMBL4956793 | 0.61 | HSP90AB1 (0.48) | ABCB1HSP90AB1 | |
| SCHEMBL9413896 | 0.59 | ABCB1 (0.53) | ABCB1HSP90AB1 | |
| Hydrochloric Acid SCHEMBL4458130 | 0.59 | HSP90AB1 (0.46) | ABCB1HSP90AB1 | |
| SCHEMBL22055448 | 0.59 | HSP90AB1 (0.46) | ABCB1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190185479-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190185479-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | PDE7B, PDE3A, PDE7A | ABCB1 1542/4885HSP90AB1 4348/4885FBP1 2772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.