Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8833118 | 0.84 | TDP1 (0.56) | TDP1SLC6A2SLC6A3KMT2AALDH1A1 | |
| SCHEMBL19917138 | 0.77 | ALDH1A1 (0.46) | TDP1SLC6A2SLC6A3KMT2AALDH1A1 | |
| SCHEMBL30777654 | 0.77 | ALDH1A1 (0.52) | TDP1SLC6A2SLC6A3KMT2AALDH1A1 | |
| SCHEMBL3042193 | 0.77 | TDP1 (0.59) | TDP1SLC6A2SLC6A3KMT2AALDH1A1 | |
| SCHEMBL6538246 | 0.76 | KDM4E (0.50) | TDP1KMT2AALDH1A1LMNATSHR | |
| SCHEMBL21138206 | 0.76 | ALDH1A1 (0.43) | TDP1SLC6A2SLC6A3KMT2AALDH1A1 | |
| SCHEMBL19917161 | 0.76 | CYP3A4 (0.45) | TDP1SLC6A2SLC6A3KMT2AALDH1A1 | |
| SCHEMBL11262327 | 0.75 | KMT2A (0.60) | TDP1SLC6A2SLC6A3KMT2AALDH1A1 | |
| SCHEMBL19917163 | 0.74 | GPBAR1 (0.43) | TDP1SLC6A2SLC6A3KMT2AALDH1A1 | |
| SCHEMBL8480122 | 0.74 | KDM4E (0.48) | TDP1KMT2AALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190185479-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190185479-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | PDE7B, PDE3A, PDE7A | TDP1 392/4885SLC6A2 1243/4885SLC6A3 1351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.