Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | SRC | P12931 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21140295 | 0.84 | NOX4 (0.47) | NOX4ALOX5MEN1KMT2ASRC | |
| SCHEMBL21139363 | 0.79 | MEN1 (0.51) | NOX4ALOX5MEN1KMT2ASRC | |
| SCHEMBL21139364 | 0.79 | SRC (0.56) | NOX4ALOX5MEN1KMT2ASRC | |
| SCHEMBL28598612 | 0.78 | NOX4 (0.64) | NOX4ALOX5MEN1KMT2ASRC | |
| SCHEMBL21139370 | 0.76 | MEN1 (0.55) | NOX4ALOX5MEN1KMT2ASRC | |
| SCHEMBL21139361 | 0.74 | SRC (0.54) | NOX4ALOX5MEN1KMT2ASRC | |
| Quercetin SCHEMBL22076795 | 0.74 | MEN1 (0.67) | NOX4ALOX5MEN1KMT2ASRC | |
| SCHEMBL21140296 | 0.72 | ESR1 (0.44) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| Curcumin SCHEMBL21049944 | 0.71 | MEN1 (0.62) | NOX4ALOX5MEN1KMT2ASRC | |
| SCHEMBL21139389 | 0.71 | MEN1 (0.54) | NOX4ALOX5MEN1KMT2ASRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019111265-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | SHARE GAL RESEARCH AND DEVELOPMENT LTD (IL) | 2019-06-13 | — | — | WO | disclosed |