⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15402202 | 0.97 | APP (0.61) | — | |
| SCHEMBL718732 | 0.83 | APP (0.42) | — | |
| Diphenylacetylene SCHEMBL68254 | 0.79 | APP (1.00) | — | |
| Diphenylacetylene SCHEMBL960609 | 0.79 | APP (1.00) | — | |
| Diphenylacetylene SCHEMBL29188592 | 0.79 | APP (1.00) | — | |
| SCHEMBL718950 | 0.79 | APP (0.38) | — | |
| Diphenylacetylene SCHEMBL23754282 | 0.76 | APP (0.92) | — | |
| Diphenylacetylene SCHEMBL31286315 | 0.76 | APP (0.92) | — | |
| Diphenylacetylene SCHEMBL9273707 | 0.76 | APP (0.92) | — | |
| Diphenylacetylene SCHEMBL31243352 | 0.76 | APP (0.92) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117845241-A | Method for preparing propargylamine compounds by electrocatalytic reaction | 中国石油化工股份有限公司 | 2024-04-09 | — | — | CN | claimed |
| US-11814462-B2 | Functionalized cyclic polymers and methods of preparing same | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2023-11-14 | — | — | US | claimed |
| CN-111592607-B | Application of covalent organic framework material of supported rhodium catalyst in alkyne polymerization | 北京理工大学 | 2023-06-20 | — | — | CN | claimed |
| CN-115521393-A | Poly (1-chloro-2-phenylacetylene) derivative and preparation method thereof | 浙江大学 | 2022-12-27 | — | — | CN | claimed |
| US-20220056167-A1 | Functionalized Cyclic Polymers and Methods of Preparing Same | NATIONAL SCIENCE FOUNDATION | 2022-02-24 | — | — | US | claimed |
| CN-111592608-B | Application of palladium source catalyst in alkyne polymerization | 北京理工大学 | 2021-07-20 | — | — | CN | claimed |
| CN-111747823-B | Polysubstituted chlorine ethynylbenzene compound and preparation method and application thereof | 华东理工大学 | 2021-04-20 | — | — | CN | claimed |
| WO-2020223672-A1 | FUNCTIONALIZED CYCLIC POLYMERS AND METHODS OF PREPARING SAME | UNIVERSITY OF FLORIDA RESEARCHFOUNDATION, INC. (US) | 2020-11-05 | — | — | WO | claimed |
| CN-109232659-B | Thermoluminescent switch material with information encryption-decryption function, preparation method and application thereof | 大连理工大学 | 2020-11-03 | — | — | CN | claimed |
| CN-111747823-A | Polysubstituted chlorine ethynylbenzene compound and preparation method and application thereof | 华东理工大学 | 2020-10-09 | — | — | CN | claimed |
| CN-103483278-B | High nitrogen glycidyl ether with electrorheological property and preparation method thereof | SHAANXI NORMAL UNIVERSITY (CN) | 2015-10-28 | — | — | CN | claimed |
| EP-2280970-B1 | IMIDAZOLIDINONE DERIVATIVES AS 11B-HSD1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2014-01-08 | — | — | EP | claimed |
| CN-103483278-A | High nitrogen glycidyl ether with electrorheological properties and preparation method thereof | UNIV SHAANXI NORMAL | 2014-01-01 | — | — | CN | claimed |
| EP-1371646-B1 | ARYL-SUBSTITUTED ALICYCLIC COMPOUND AND MEDICAL COMPOSITION COMPRISING THE SAME | DAINIPPON SUMITOMO PHARMA CO (JP) | 2010-05-19 | — | — | EP | claimed |
| EP-0404029-B1 | Substantially odor free, UV curable organopolysiloxane release coating compositions and coating method | GEN ELECTRIC (US) | 1994-02-16 | — | — | EP | claimed |
| EP-0449439-A1 | Process for formation of resist patterns | FUJITSU LIMITED (JP) | 1991-10-02 | — | — | EP | claimed |
| US-4381310-A | Antimycotic substituted 2,4-dichlorophenyl-imidazolyl-vinyl-carbinols | BAYER AKTIENGESELLSCHAFT (DE) | 1983-04-26 | — | — | US | claimed |
| EP-0048828-A1 | Substituted 2,4-dichlorophenyl-imidazolyl-vinyl carbinols, process for their preparation and antimicrobial agents containing these compounds | BAYER AG (DE) | 1982-04-07 | — | — | EP | claimed |
| EP-0048827-A1 | Substituted 2,4-dichlorophenyl-imidazolyl-vinyl ketones, processes for their preparation and antimicrobial agents containing these compounds | BAYER AG (DE) | 1982-04-07 | — | — | EP | claimed |
| US-4210610-A | CHLOROARYLHYDROXY SUBSTITUTED ACETYLENES | GULF RESEARCH AND DEVELOPMENT COMPANY (US) | 1980-07-01 | — | — | US | claimed |