SCHEMBL21141344

SCHEMBL21141344

c1ccc(C2(c3ccccc3)c3ccccc3-c3ccc(N(c4ccc5c(c4)-c4ccccc4-c4ccccc4-c4ccccc4-5)c4cccc5c4oc4ccccc45)cc32)cc1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.37
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
OPRK1 P41145 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16996174 0.97 ALOX5 (0.39) ALOX5KDM4EMEN1LMNAMAPT
SCHEMBL17854348 0.96 ALOX5 (0.37) ALOX5KDM4EMEN1LMNAMAPT
SCHEMBL25145360 0.96 ALOX5 (0.38) ALOX5KDM4EMEN1LMNAMAPT
SCHEMBL25145819 0.95 ALOX5 (0.36) ALOX5KDM4EMEN1LMNAMAPT
SCHEMBL17854402 0.95 ALOX5 (0.36) ALOX5KDM4EMEN1LMNAMAPT
SCHEMBL16882701 0.95 ALOX5 (0.38) ALOX5KDM4EMEN1LMNAMAPT
SCHEMBL17804881 0.95 ALOX5 (0.38) ALOX5KDM4EMEN1LMNAMAPT
SCHEMBL16882708 0.95 ALOX5 (0.39) ALOX5KDM4EMEN1LMNAMAPT
SCHEMBL17805101 0.94 ALOX5 (0.37) ALOX5KDM4EMEN1LMNAMAPT
SCHEMBL21141155 0.93 ALOX5 (0.40) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11512038-B2 Tetraphenylene triarylamine compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-11-29 US disclosed
US-20190185412-A1 TETRAPHENYLENE TRIARYLAMINE COMPOUNDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11512038-B2 Tetraphenylene triarylamine compounds OCIAD2, OCIAD1, SLC7A5 ALOX5 963/4885KDM4E 4100/4885MEN1 3882/4885
US-20190185412-A1 TETRAPHENYLENE TRIARYLAMINE COMPOUNDS OCIAD2, OCIAD1, SLC7A5 ALOX5 963/4885KDM4E 4100/4885MEN1 3882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.