Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PGK2 | P07205 | 1/20 | 0.30 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124155 | 0.98 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL4450401 | 0.98 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL16567918 | 0.98 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL7635668 | 0.95 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL21752929 | 0.95 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL21752847 | 0.95 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL21145174 | 0.95 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL15271354 | 0.95 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL7634708 | 0.95 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAALDH1A1KDM4EDUSP3 | |
| Water SCHEMBL2477276 | 0.95 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAALDH1A1KDM4EDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3996662-A1 | METHODS AND COMPOSITIONS TO INCREASE THE HARDNESS AND RESISTANCE OF ENAMEL | The Procter & Gamble Company (US) | 2022-05-18 | — | — | EP | disclosed |
| CN-114173747-A | Method and composition for improving enamel hardness and resistance | 宝洁公司 | 2022-03-11 | — | — | CN | disclosed |
| WO-2021007196-A1 | METHODS AND COMPOSITIONS TO INCREASE THE HARDNESS AND RESISTANCE OF ENAMEL | THE PROCTER & GAMBLE COMPANY (US) | 2021-01-14 | — | — | WO | disclosed |
| US-20210007948-A1 | Methods And Compositions To Increase The Hardness And Resistance Of Enamel | THE PROCTER & GAMBLE COMPANY | 2021-01-14 | — | — | US | disclosed |
| EP-3740184-A1 | METHODS AND COMPOSITIONS TO INCREASE THE HARDNESS AND RESISTANCE OF ENAMEL | The Procter & Gamble Company (US) | 2020-11-25 | — | — | EP | disclosed |
| CN-111615378-A | Method and composition for improving enamel hardness and resistance | 宝洁公司 | 2020-09-01 | — | — | CN | disclosed |
| US-10588833-B2 | Methods and compositions to increase the hardness and resistance of enamel | THE PROCTER & GAMBLE COMPANY (US) | 2020-03-17 | — | — | US | disclosed |
| WO-2019143746-A1 | METHODS AND COMPOSITIONS TO INCREASE THE HARDNESS AND RESISTANCE OF ENAMEL | THE PROCTER & GAMBLE COMPANY (US) | 2019-07-25 | — | — | WO | disclosed |
| US-20190216693-A1 | Methods And Compositions TO Increase The Hardness And Resistance of Enamel | THE PROCTER & GAMBLE COMPANY | 2019-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190216693-A1 | Methods And Compositions TO Increase The Hardness And Resistance of Enamel | CHD3, CHD9, CHD1 | SMN1; SMN2 2809/4885LMNA 639/4885ALDH1A1 4121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.