SCHEMBL21145733

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21145734	1.00	NTRK1 (0.65)	NTRK1MEN1KMT2AKDM4ECYP3A4
	SCHEMBL1639836	0.89	MEN1 (0.72)	NTRK1MEN1KMT2AKDM4ECYP3A4
	SCHEMBL12767340	0.89	MEN1 (0.72)	NTRK1MEN1KMT2AKDM4ECYP3A4
	SCHEMBL1639834	0.89	MEN1 (0.72)	NTRK1MEN1KMT2AKDM4ECYP3A4
	SCHEMBL29695425	0.89	NTRK1 (0.81)	NTRK1MEN1KMT2AKDM4ECYP3A4
	SCHEMBL1639422	0.89	NTRK1 (0.81)	NTRK1MEN1KMT2AKDM4ECYP3A4
	SCHEMBL1639424	0.89	NTRK1 (0.81)	NTRK1MEN1KMT2AKDM4ECYP3A4
	SCHEMBL10049700	0.89	NTRK1 (0.81)	NTRK1MEN1KMT2AKDM4ECYP3A4
	SCHEMBL13952237	0.87	NOX4 (0.71)	NTRK1MEN1KMT2AKDM4ECYP3A4
	SCHEMBL21145742	0.85	KDM4E (0.70)	MEN1KMT2AKDM4EMAPK1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.