Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24086863 | 1.00 | LMNA (0.50) | LMNACYP2C9OPRL1CHRM2CHRM1 | |
| SCHEMBL23475182 | 1.00 | LMNA (0.50) | LMNACYP2C9OPRL1CHRM2CHRM1 | |
| SCHEMBL23475186 | 1.00 | LMNA (0.50) | LMNACYP2C9OPRL1CHRM2CHRM1 | |
| SCHEMBL23475246 | 1.00 | LMNA (0.50) | LMNACYP2C9OPRL1CHRM2CHRM1 | |
| SCHEMBL21145986 | 1.00 | LMNA (0.50) | LMNACYP2C9OPRL1CHRM2CHRM1 | |
| SCHEMBL21145769 | 0.91 | LMNA (0.61) | LMNACYP2C9OPRL1CHRM2CHRM1 | |
| SCHEMBL17880968 | 0.91 | LMNA (0.61) | LMNACYP2C9OPRL1CHRM2CHRM1 | |
| SCHEMBL24487371 | 0.91 | LMNA (0.61) | LMNACYP2C9OPRL1CHRM2CHRM1 | |
| SCHEMBL24487303 | 0.91 | LMNA (0.61) | LMNACYP2C9OPRL1CHRM2CHRM1 | |
| SCHEMBL13676329 | 0.91 | LMNA (0.61) | LMNACYP2C9OPRL1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118358-A1 | HEPATITIS B CAPSID ASSEMBLY MODULATORS | VenatoRx Pharmaceuticals, Inc. (US) | 2019-06-20 | — | — | WO | disclosed |