SCHEMBL21145993

SCHEMBL21145993

CC(C)N1[C@@H]2COC[C@H]1C[C@@H](O)C2

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
CYP2C9 P11712 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21145980 1.00 LMNA (0.43) LMNACYP2C9
SCHEMBL23475240 1.00 LMNA (0.43) LMNACYP2C9
SCHEMBL21146011 1.00 LMNA (0.43) LMNACYP2C9
SCHEMBL23475238 1.00 LMNA (0.43) LMNACYP2C9
SCHEMBL14208073 0.86
SCHEMBL16249769 0.86
SCHEMBL26238392 0.81 LMNA (0.50) LMNACYP2C9
SCHEMBL24117892 0.81
SCHEMBL15679993 0.80
SCHEMBL23475181 0.79 LMNA (0.61) LMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019118358-A1 HEPATITIS B CAPSID ASSEMBLY MODULATORS VenatoRx Pharmaceuticals, Inc. (US) 2019-06-20 WO disclosed