SCHEMBL2114733

SCHEMBL2114733

NCCCC(NC(=O)CN)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.54
SLC15A2 Q16348 1/20 0.51
GNPAT O15228 1/20 0.50
SLC6A5 Q9Y345 1/20 0.49
NOD1 Q9Y239 5/20 0.45
CPB2 Q96IY4 2/20 0.42
GSR P00390 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
RNPEP Q9H4A4 1/20 0.39
RIMKLA Q8IXN7 1/20 0.39
NAALAD2 Q9Y3Q0 1/20 0.39
ITGB3 P05106 1/20 0.39
ITGA2B P08514 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2114736 1.00 FOLH1 (0.54) FOLH1SLC15A2GNPATSLC6A5NOD1
SCHEMBL27860271 1.00 FOLH1 (0.54) FOLH1SLC15A2GNPATSLC6A5NOD1
SCHEMBL1455499 0.94 FOLH1 (0.62) FOLH1SLC15A2GNPATSLC6A5NOD1
SCHEMBL3460653 0.94 FOLH1 (0.62) FOLH1SLC15A2GNPATSLC6A5NOD1
SCHEMBL1455498 0.94 FOLH1 (0.62) FOLH1SLC15A2GNPATSLC6A5NOD1
SCHEMBL27814763 0.93 SLC15A2 (0.56) FOLH1SLC15A2GNPATSLC6A5NOD1
SCHEMBL27814755 0.93 SLC15A2 (0.56) FOLH1SLC15A2GNPATSLC6A5NOD1
Ammonia Solution, Strong SCHEMBL4293159 0.92 FOLH1 (0.60) FOLH1SLC15A2GNPATSLC6A5NOD1
Ammonia Solution, Strong SCHEMBL4293156 0.92 FOLH1 (0.60) FOLH1SLC15A2GNPATSLC6A5NOD1
SCHEMBL30964327 0.88 SLC15A2 (0.62) FOLH1SLC15A2GNPATSLC6A5CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100055088-A1 CXCR4 Antagonists for Wound Healing and Re-Epithelialization HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) 2010-03-04 US claimed
EP-1898943-A2 CXCR4 ANTAGONISTS FOR WOUND HEALING AND RE-EPITHELIALIZATION Hadasit Medical Research Services & Development Ltd. (IL) 2008-03-19 EP claimed
WO-2006126188-A2 CXCR4 ANTAGONISTS FOR WOUND HEALING AND RE-EPITHELIALIZATION HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) 2006-11-30 WO claimed
US-20040116655-A1 Novel polypeptides and anti-hiv drugs containing the same BIOKINE THERAPEUTICS LTD. (IL) 2004-06-17 US claimed
EP-1323730-A1 NOVEL POLYPEPTIDES AND ANTI-HIV DRUGS CONTAINING THE SAME SEIKAGAKU CORPORATION (JP) 2003-07-02 EP claimed
EP-0677061-B1 POLYPEPTIDES AND ANTI-HIV AGENTS PREPARED THEREFROM SEIKAGAKU KOGYO CO LTD (JP) 1999-03-03 EP claimed
US-5776899-A Polypeptide and anti-HIV agent prepared therefrom SEIKAGAKU CORPORATION (JP) 1998-07-07 US claimed
CN-1038841-C Polypeptide and anti-hiv agent prepared therefrom SEIKAGAKU CO (JP) 1998-06-24 CN claimed
CN-1116427-A Novel polypeptide and anti-HIV agent prepared from the same SEIKAGAKU KOGYO CO LTD (JP) 1996-02-07 CN claimed
EP-0677061-A1 POLYPEPTIDE AND ANTI-HIV AGENT PREPARED THEREFROM SEIKAGAKU CORPORATION (JP) 1995-10-18 EP claimed
WO-1995010534-A1 POLYPEPTIDE AND ANTI-HIV AGENT PREPARED THEREFROM SEIKAGAKU CORPORATION (JP) 1995-04-20 WO claimed
EP-3011961-B1 4F-BENZOYL-TN14003 FOR THE MOBILISATION OF HEMATOPOIETIC PROGENITOR CELLS IN VIEW OF TRANSPLANTATION BIOKINE THERAPEUTICS LTD (IL) 2020-11-11 EP disclosed
EP-2841084-B1 CXCR4 ANTAGONIST PEPTIDE FOR USE IN THE TREATMENT OF LARGE CELL LUNG CANCER BIOKINE THERAPEUTICS LTD (IL) 2018-05-30 EP disclosed
US-9439942-B2 Peptides and use thereof in the treatment of large cell lung cancer BIOKINE THERAPEUTICS LTD. (IL) 2016-09-13 US disclosed
US-9427456-B2 Peptide therapy for increasing platelet levels BIOKINE THERAPEUTICS LTD. (IL) 2016-08-30 US disclosed
CN-1116427-A Novel polypeptide and anti-HIV agent prepared from the same SEIKAGAKU KOGYO CO LTD (JP) 1996-02-07 CN disclosed
EP-0677061-A1 POLYPEPTIDE AND ANTI-HIV AGENT PREPARED THEREFROM SEIKAGAKU CORPORATION (JP) 1995-10-18 EP disclosed
EP-0677061-A1 POLYPEPTIDE AND ANTI-HIV AGENT PREPARED THEREFROM SEIKAGAKU CORPORATION (JP) 1995-10-18 EP disclosed
WO-1995010534-A1 POLYPEPTIDE AND ANTI-HIV AGENT PREPARED THEREFROM SEIKAGAKU CORPORATION (JP) 1995-04-20 WO disclosed
WO-1995010534-A1 POLYPEPTIDE AND ANTI-HIV AGENT PREPARED THEREFROM SEIKAGAKU CORPORATION (JP) 1995-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100055088-A1 CXCR4 Antagonists for Wound Healing and Re-Epithelialization CXCR4, CXCL12, CXCR5 FOLH1 3082/4885SLC15A2 317/4885GNPAT 3883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.