Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL4293159

N.NCCCC[C@H](NC(=O)CN)C(=O)O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.60
SLC15A2 Q16348 1/20 0.55
SLC6A5 Q9Y345 1/20 0.54
GNPAT O15228 1/20 0.47
GSR P00390 1/20 0.47
RNPEP Q9H4A4 1/20 0.46
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CPB2 Q96IY4 8/20 0.43
NOD1 Q9Y239 2/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL4293156 1.00 FOLH1 (0.60) FOLH1SLC15A2SLC6A5GNPATGSR
SCHEMBL3460653 0.98 FOLH1 (0.62) FOLH1SLC15A2SLC6A5GNPATGSR
SCHEMBL1455498 0.98 FOLH1 (0.62) FOLH1SLC15A2SLC6A5GNPATGSR
SCHEMBL1455499 0.98 FOLH1 (0.62) FOLH1SLC15A2SLC6A5GNPATGSR
SCHEMBL27860271 0.92 FOLH1 (0.54) FOLH1SLC15A2SLC6A5GNPATGSR
SCHEMBL2114733 0.92 FOLH1 (0.54) FOLH1SLC15A2SLC6A5GNPATGSR
SCHEMBL2114736 0.92 FOLH1 (0.54) FOLH1SLC15A2SLC6A5GNPATGSR
SCHEMBL30964327 0.91 SLC15A2 (0.62) FOLH1SLC15A2SLC6A5GNPATGSR
SCHEMBL30371073 0.91 SLC15A2 (0.62) FOLH1SLC15A2SLC6A5GNPATGSR
SCHEMBL29532146 0.87 SLC15A2 (0.58) FOLH1SLC15A2SLC6A5GNPATCPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113227124-B Compounds having affinity substance, cleavage moiety and reactive group for antibody or salts thereof 味之素株式会社 2025-04-08 CN disclosed
CN-117377501-A Radioactive antineoplastic agent 日本医事物理股份有限公司 2024-01-09 CN disclosed
CN-116829573-A Compounds or salts thereof, and antibodies derived therefrom 味之素株式会社 2023-09-29 CN disclosed
US-11149074-B2 Azide group-containing Fc protein AJINOMOTO CO., INC. (JP) 2021-10-19 US disclosed
CN-113227124-A Compound having affinity substance, cleavable moiety and reactive group for antibody, or salt thereof 味之素株式会社 2021-08-06 CN disclosed
CN-112262152-A Compound having affinity substance, cleavable moiety and reactive group for antibody, or salt thereof 味之素株式会社 2021-01-22 CN disclosed
EP-2959896-B1 USE OF DCP-LA AS REAGENT FOR INHIBITING PHOSPHATASE 1B IN VITRO NISHIZAKI BIOINFORMATION RES INSTITUTE (JP) 2020-09-23 EP disclosed
US-10597427-B2 Diabetes-inducible bacterium AJINOMOTO CO., INC. (JP) 2020-03-24 US disclosed
EP-2641891-B1 PKC-epsilon ACTIVATOR NISHIZAKI BIOINFORMATION RES INSTITUTE (JP) 2019-07-03 EP disclosed
US-10251897-B2 GLUT4 endocytosis inhibitor NISHIZAKI BIOINFORMATION RESEARCH INSTITUTE (JP) 2019-04-09 US disclosed
EP-2915881-A1 FIBROTIC NON-HUMAN ANIMAL, AND USE THEREOF Kyoto University (JP) 2015-09-09 EP disclosed
US-9012500-B2 PKC-ε activator NISHIZAKI BIOINFORMATION RESEARCH INSTITUTE (JP) 2015-04-21 US disclosed
US-20150079209-A1 DIABETES-INDUCIBLE BACTERIUM AJINOMOTO CO., INC. (JP) 2015-03-19 US disclosed
EP-2832859-A1 DIABETES-INDUCIBLE BACTERIUM Ajinomoto Co., Inc. (JP) 2015-02-04 EP disclosed
US-20130331454-A1 PKC-EPSILON ACTIVATOR NISHIZAKI BIOINFORMATION RESEARCH INSTITUTE (JP) 2013-12-12 US disclosed
EP-2659892-A1 CONCOMITANT DRUG FOR IMPROVING COGNITIVE FUNCTION Nishizaki Bioinformation Research Institute (JP) 2013-11-06 EP disclosed
US-20130274228-A1 CONCOMITANT DRUG FOR IMPROVING COGNITIVE FUNCTION NISHIZAKI BIOINFORMATION RESEARCH INSTITUTE (JP) 2013-10-17 US disclosed
EP-2641891-A1 PKC- ACTIVATOR Nishizaki Bioinformation Research Institute (JP) 2013-09-25 EP disclosed
US-20120196282-A1 METHOD OF REGENERATING ELASTIC FIBER AND SCREENING METHOD NB HEALTH LABORATORY CO. LTD. (JP) 2012-08-02 US disclosed
US-20090233281-A1 DIAGNOSTIC MARKER FOR ALLERGY RIKEN (JP) 2009-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130331454-A1 PKC-EPSILON ACTIVATOR PRKCZ, PRKCA, PRKCQ FOLH1 2397/4885SLC15A2 2445/4885SLC6A5 586/4885
US-10251897-B2 GLUT4 endocytosis inhibitor SLC2A4, SLC2A1, SLC2A3 FOLH1 2798/4885SLC15A2 159/4885SLC6A5 410/4885
US-11149074-B2 Azide group-containing Fc protein FCGRT, FCGR1A, FCGR3B FOLH1 750/4885SLC15A2 2350/4885SLC6A5 1824/4885
US-20130274228-A1 CONCOMITANT DRUG FOR IMPROVING COGNITIVE FUNCTION LPCAT1, LPCAT3, CPT1A FOLH1 643/4885SLC15A2 2591/4885SLC6A5 1434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.