SCHEMBL21147966

SCHEMBL21147966

c1ccc2c(c1)oc1c(-c3cccc4c3oc3c(-n5c6ccccc6c6ccccc65)cc(-n5c6ccccc6c6ccccc65)cc34)cccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.46
PRKDC P78527 5/20 0.40
PIK3CD O00329 1/20 0.37
PIK3CB P42338 1/20 0.37
ATM Q13315 2/20 0.37
KDM4E B2RXH2 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
AHR P35869 1/20 0.35
GGPS1 O95749 1/20 0.34
HDAC8 Q9BY41 1/20 0.33
PTGES2 Q9H7Z7 1/20 0.32
MEN1 O00255 2/20 0.32
CYP2C19 P33261 2/20 0.32
KMT2A Q03164 2/20 0.32
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9890181 0.91 KDM4E (0.39) ALOX5PRKDCATMKDM4EL3MBTL1
SCHEMBL5028256 0.91 KDM4E (0.43) ALOX5ATMKDM4EL3MBTL1AHR
SCHEMBL26536780 0.89 ALOX5 (0.50) ALOX5PRKDCPIK3CDPIK3CBATM
SCHEMBL21147969 0.88 ALOX5 (0.37) ALOX5PRKDCPIK3CDPIK3CBATM
SCHEMBL21583611 0.86 ALOX5 (0.49) ALOX5PRKDCPIK3CDPIK3CBATM
SCHEMBL12925588 0.86 ALOX5 (0.45) ALOX5PRKDCPIK3CDPIK3CBATM
SCHEMBL5030361 0.85 ALOX5 (0.46) ALOX5PRKDCPIK3CDPIK3CBATM
SCHEMBL9890112 0.85 AHR (0.41) ALOX5ATMKDM4EL3MBTL1AHR
SCHEMBL10038503 0.85 KDM4E (0.43) ATMKDM4EL3MBTL1AHRMEN1
SCHEMBL5028281 0.85 KDM4E (0.48) ATMKDM4EL3MBTL1MEN1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11767324-B2 Compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2023-09-26 US disclosed
WO-2020197253-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 2020-10-01 WO disclosed
WO-2019190248-A9 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 2020-04-02 WO disclosed
WO-2019190235-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2019-10-03 WO disclosed
WO-2019190248-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 2019-10-03 WO disclosed
WO-2019135633-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2019-07-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11767324-B2 Compound and organic light-emitting device comprising same CCNL2, DRD1, CCNA1 ALOX5 2310/4885PRKDC 4653/4885PIK3CD 4647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.