SCHEMBL21148181

SCHEMBL21148181

c1ccc2c(c1)oc1cc(-c3nc(-c4ccc(-c5cccc6oc7ccccc7c56)cc4)nc(-c4cccc5oc6ccccc6c45)n3)ccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.41
HCRTR1 O43613 1/20 0.40
KDM4E B2RXH2 4/20 0.40
ALDH1A1 P00352 4/20 0.40
HPGD P15428 4/20 0.40
MEN1 O00255 3/20 0.40
MAPT P10636 3/20 0.40
KMT2A Q03164 3/20 0.40
BACE1 P56817 1/20 0.39
ALOX5 P09917 1/20 0.39
HSD17B10 Q99714 2/20 0.37
GAA P10253 1/20 0.37
PRKDC P78527 1/20 0.36
KIT P10721 1/20 0.35
KDR P35968 1/20 0.35
FLT3 P36888 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 1/20 0.35
TTR P02766 1/20 0.35
HTR2B P41595 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24217263 0.96 HCRTR1 (0.40) AHRHCRTR1KDM4EALDH1A1HPGD
SCHEMBL25089938 0.96 ALOX5 (0.43) AHRHCRTR1KDM4EALDH1A1HPGD
SCHEMBL21148608 0.96 AHR (0.44) AHRHCRTR1KDM4EALDH1A1HPGD
SCHEMBL23913891 0.96 AHR (0.44) AHRHCRTR1KDM4EALDH1A1HPGD
SCHEMBL23823729 0.95 HCRTR1 (0.40) AHRHCRTR1KDM4EALDH1A1HPGD
SCHEMBL24217265 0.95 HCRTR1 (0.39) AHRHCRTR1KDM4EALDH1A1HPGD
SCHEMBL22763864 0.95 HCRTR1 (0.39) AHRHCRTR1KDM4EALDH1A1HPGD
SCHEMBL23821763 0.95 ALOX5 (0.40) AHRHCRTR1KDM4EALDH1A1HPGD
SCHEMBL24097369 0.95 ALOX5 (0.40) AHRHCRTR1KDM4EALDH1A1HPGD
SCHEMBL23820770 0.94 AHR (0.41) AHRHCRTR1KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 AHR 1916/4885HCRTR1 231/4885KDM4E 4500/4885
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 AHR 1916/4885HCRTR1 231/4885KDM4E 4500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.