SCHEMBL2114824

SCHEMBL2114824

C=C(C)C(=O)OCC(F)(F)S(=O)(=O)O.FS(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.36
KMT2A Q03164 3/20 0.36
MEN1 O00255 1/20 0.36
TSHR P16473 1/20 0.36
NR1I2 O75469 1/20 0.33
ELANE P08246 1/20 0.33
MAPT P10636 3/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HSD11B1 P28845 3/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ALDH1A1 P00352 3/20 0.32
ATM Q13315 1/20 0.32
KAT6A Q92794 1/20 0.31
MAPK1 P28482 1/20 0.31
GAA P10253 2/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1261674 0.86 ELANE (0.34) HTTKMT2AMEN1TSHRELANE
SCHEMBL2624987 0.83 TSHR (0.41) TSHRALDH1A1L3MBTL1
SCHEMBL543947 0.82 TSHR (0.40) TSHRALDH1A1
SCHEMBL10004168 0.81 ELANE (0.32) HTTELANEPOLBAPEX1TDP1
SCHEMBL6116870 0.81 HSD11B1 (0.32) HTTKMT2AMEN1TSHRELANE
SCHEMBL246811 0.80 KMT2A (0.36) HTTKMT2AMEN1TSHRNR1I2
SCHEMBL2114823 0.79 MEN1 (0.30) HTTKMT2AMEN1TSHR
Thiophene SCHEMBL28212720 0.79 TSHR (0.33) TSHRALDH1A1
SCHEMBL28289801 0.77 ELANE (0.38) HTTKMT2AMEN1TSHRELANE
SCHEMBL28344662 0.76 HTT (0.35) HTTKMT2AMEN1TSHRNR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8158327-B2 Onium salt compound, polymer compound comprising the salt compound, chemically amplified resist composition comprising the polymer compound, and method for patterning using the composition KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2012-04-17 US disclosed
US-20100075256-A1 Onium salt compound, polymer compound comprising the salt compound, chemically amplified resist composition comprising the polymer compound, and method for patterning using the composition KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2010-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100075256-A1 Onium salt compound, polymer compound comprising the salt compound, chemically amplified resist composition comprising the polymer compound, and method for patterning using the composition ARF5, ARL1, FGFR2 HTT 3584/4885KMT2A 566/4885MEN1 3295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.