SCHEMBL21148722

SCHEMBL21148722

c1cc(-c2nc(-c3cccc(-c4cccc5sc6ccccc6c45)c3)nc(-c3cccc4ccccc34)n2)cc(-c2cccc3sc4ccccc4c23)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.38
ALDH1A1 P00352 4/20 0.38
MAPT P10636 4/20 0.38
HPGD P15428 4/20 0.38
SMN1; SMN2 Q16637 4/20 0.38
MAPK1 P28482 3/20 0.38
HSD17B10 Q99714 3/20 0.38
TP53 P04637 2/20 0.38
TSHR P16473 1/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
LIMK1 P53667 1/20 0.36
F9 P00740 1/20 0.35
ALOX5 P09917 1/20 0.35
GPR3 P46089 1/20 0.34
BRDT Q58F21 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21148705 0.95 ALDH1A1 (0.40) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL21149133 0.94 ALDH1A1 (0.36) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL21148248 0.93 LIMK1 (0.38) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL21148484 0.93 F9 (0.34) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL21148185 0.91 F9 (0.41) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL24266637 0.90 LIMK1 (0.39) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL21563853 0.90 LIMK1 (0.39) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL21148195 0.90 LIMK1 (0.41) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL25000307 0.90 LIMK1 (0.41) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL24523519 0.89 KDM4E (0.38) KDM4EALDH1A1MAPTHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 KDM4E 4500/4885ALDH1A1 191/4885MAPT 1761/4885
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 KDM4E 4500/4885ALDH1A1 191/4885MAPT 1761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.