SCHEMBL21148729

SCHEMBL21148729

c1ccc(-c2ccc(-c3cc(-c4ccc(-c5cccc6sc7ccccc7c56)cc4)nc(-c4ccc5sc6ccccc6c5c4)n3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.40
KMT2A Q03164 5/20 0.40
MAPT P10636 4/20 0.40
ALDH1A1 P00352 3/20 0.40
HPGD P15428 3/20 0.40
KDM4E B2RXH2 2/20 0.40
LMNA P02545 2/20 0.40
NTSR1 P30989 1/20 0.38
PIM3 Q86V86 1/20 0.38
GLA P06280 1/20 0.37
LIMK1 P53667 1/20 0.36
ACACA Q13085 3/20 0.35
F9 P00740 1/20 0.35
ALOX5 P09917 1/20 0.35
CYP1A2 P05177 1/20 0.34
MAOB P27338 2/20 0.34
ROCK1 Q13464 1/20 0.34
MAOA P21397 1/20 0.34
GPR3 P46089 1/20 0.34
DHODH Q02127 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21149122 0.93 MEN1 (0.41) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL21149178 0.93 PIM3 (0.39) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL21149227 0.93 MEN1 (0.41) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL21149229 0.93 MEN1 (0.41) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL21149157 0.92 MEN1 (0.45) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL21149248 0.92 MEN1 (0.45) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL21148255 0.91 PIM3 (0.38) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL22329843 0.91 MEN1 (0.44) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL20982339 0.91 LIMK1 (0.38) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL15501431 0.91 MEN1 (0.46) MEN1KMT2AMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 MEN1 2271/4885KMT2A 4362/4885MAPT 1761/4885
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 MEN1 2271/4885KMT2A 4362/4885MAPT 1761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.