SCHEMBL21148255

SCHEMBL21148255

c1ccc(-c2ccc(-c3cc(-c4ccc5sc6ccccc6c5c4)nc(-c4cccc5sc6ccccc6c45)n3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM3 Q86V86 1/20 0.38
MEN1 O00255 7/20 0.38
KMT2A Q03164 7/20 0.38
ALDH1A1 P00352 5/20 0.38
HPGD P15428 5/20 0.38
MAPT P10636 4/20 0.38
KDM4E B2RXH2 3/20 0.38
LMNA P02545 2/20 0.38
GLA P06280 1/20 0.38
NTSR1 P30989 1/20 0.36
ALOX5 P09917 1/20 0.36
CYP1A2 P05177 1/20 0.35
ROCK1 Q13464 1/20 0.35
GPR3 P46089 1/20 0.35
DHODH Q02127 1/20 0.35
TSHR P16473 2/20 0.34
ATM Q13315 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
CYP1A1 P04798 1/20 0.34
CYP1B1 Q16678 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21149159 0.94 MEN1 (0.41) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL21149274 0.93 MEN1 (0.38) PIM3MEN1KMT2AALDH1A1HPGD
SCHEMBL21148714 0.92 ALOX5 (0.37) PIM3MEN1KMT2AALDH1A1HPGD
SCHEMBL21148729 0.91 MEN1 (0.40) PIM3MEN1KMT2AALDH1A1HPGD
SCHEMBL19802446 0.91 PIM3 (0.40) PIM3MEN1KMT2AALDH1A1HPGD
SCHEMBL19802439 0.91 PIM3 (0.40) PIM3MEN1KMT2AALDH1A1HPGD
SCHEMBL19802969 0.91 MEN1 (0.41) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL22876324 0.90 PIM3 (0.37) PIM3MEN1KMT2AALDH1A1HPGD
SCHEMBL22330254 0.90 MEN1 (0.47) PIM3MEN1KMT2AALDH1A1HPGD
SCHEMBL19802434 0.90 PIM3 (0.40) PIM3MEN1KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 PIM3 3857/4885MEN1 2271/4885KMT2A 4362/4885
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 PIM3 3857/4885MEN1 2271/4885KMT2A 4362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.