Sugi Predict

Sugi Predict / Compounds / SCHEMBL21149134

SCHEMBL21149134

SCHEMBL21149134

c1cc(-c2nc(-c3ccc4ccccc4c3)nc(-c3cc4ccccc4c4ccccc34)n2)cc(-c2cccc3sc4ccccc4c23)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ S1PR5 Q9H228 8/20 0.38
▸ S1PR4 O95977 6/20 0.38
▸ ALDH1A1 P00352 2/20 0.35
▸ HSD17B10 Q99714 2/20 0.35
▸ HPGD P15428 1/20 0.35
▸ TSHR P16473 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ CASP1 P29466 1/20 0.35
▸ HIF1A Q16665 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ CYP11B1 P15538 1/20 0.34
▸ GPR84 Q9NQS5 1/20 0.34
▸ ALOX5 P09917 1/20 0.33
▸ GSTP1 P09211 1/20 0.33
▸ PIM1 P11309 1/20 0.32
▸ LIMK1 P53667 1/20 0.32
▸ HDAC4 P56524 1/20 0.32
▸ HDAC2 Q92769 1/20 0.32
▸ HDAC8 Q9BY41 1/20 0.32
▸ HSD17B1 P14061 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21148490 0.94 S1PR5 (0.37) S1PR5S1PR4ALDH1A1HSD17B10HPGD
SCHEMBL26231386 0.94 S1PR5 (0.35) S1PR5S1PR4ALDH1A1HSD17B10HPGD
SCHEMBL21148499 0.94 S1PR5 (0.36) S1PR5S1PR4ALDH1A1HSD17B10HPGD
SCHEMBL21149176 0.94 S1PR5 (0.37) S1PR5S1PR4ALDH1A1HSD17B10HPGD
SCHEMBL21148721 0.94 ALDH1A1 (0.39) ALDH1A1HSD17B10HPGDTSHRMAPK1
SCHEMBL21149132 0.94 ALDH1A1 (0.39) ALDH1A1HSD17B10HPGDTSHRMAPK1
SCHEMBL21148589 0.92 ALDH1A1 (0.35) S1PR5S1PR4ALDH1A1HSD17B10HPGD
SCHEMBL21149133 0.91 ALDH1A1 (0.36) ALDH1A1HSD17B10HPGDTSHRMAPK1
SCHEMBL21148726 0.91 F9 (0.36) S1PR5S1PR4ALDH1A1HSD17B10HPGD
SCHEMBL23759502 0.90 S1PR5 (0.37) S1PR5S1PR4ALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 — — US disclosed
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 — — US disclosed
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2019-07-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 S1PR5 3651/4885S1PR4 3107/4885ALDH1A1 191/4885
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 S1PR5 3651/4885S1PR4 3107/4885ALDH1A1 191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.