SCHEMBL21149622

SCHEMBL21149622

Cc1cccc(N(Cc2ccccc2)c2ccc(N(c3ccc(N(C4=CC(C)CC=C4)c4ccccc4)cc3)c3ccc(N(c4ccccc4)c4cccc(C)c4)cc3)cc2)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.36
NPC1 O15118 2/20 0.36
ALDH1A1 P00352 2/20 0.36
JAK2 O60674 1/20 0.36
HTT P42858 1/20 0.36
PAX8 Q06710 1/20 0.36
NR3C2 P08235 1/20 0.33
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
CYP2C19 P33261 1/20 0.32
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
AR P10275 1/20 0.31
MAPT P10636 1/20 0.31
NR1H4 Q96RI1 1/20 0.30
TSPO P30536 1/20 0.30
ABL1 P00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25530728 0.89 HPGD (0.34) RAB9ANPC1ALDH1A1JAK2HTT
SCHEMBL12138153 0.89 HPGD (0.34) RAB9ANPC1ALDH1A1JAK2HTT
SCHEMBL13808808 0.86 HPGD (0.32)
SCHEMBL12776035 0.86 HPGD (0.32)
SCHEMBL19051665 0.83 HPGD (0.31)
SCHEMBL10066022 0.82 NPC1 (0.39) RAB9ANPC1ALDH1A1KMT2AMEN1
SCHEMBL19048804 0.82 RAB9A (0.49) RAB9ANPC1ALDH1A1JAK2HTT
SCHEMBL12700630 0.81 HPGD (0.32) LMNACYP2C19MAPT
SCHEMBL18828697 0.79 HPGD (0.30)
SCHEMBL19060605 0.79 HPGD (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2290694-B1 Image pickup device and image pickup apparatus FUJIFILM CORP (JP) 2019-07-10 EP disclosed