SCHEMBL21149877

SCHEMBL21149877

O=C(NO)C(CCc1ccccc1)N1C(=O)c2ccccc2C1=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.57
ALDH1A1 P00352 4/20 0.56
GAA P10253 2/20 0.56
POLB P06746 3/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
KDM4E B2RXH2 1/20 0.51
TP53 P04637 1/20 0.51
GLA P06280 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
HPGD P15428 1/20 0.51
ALOX12 P18054 1/20 0.51
NFKB1 P19838 1/20 0.51
APEX1 P27695 1/20 0.51
MAPK1 P28482 1/20 0.51
HSD17B10 Q99714 1/20 0.51
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
MMP8 P22894 2/20 0.49
PKM P14618 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22570463 1.00 TSHR (0.57) TSHRALDH1A1GAAPOLBL3MBTL1
SCHEMBL11619526 0.85 ALDH1A1 (0.72) TSHRALDH1A1GAAPOLBL3MBTL1
SCHEMBL22556214 0.85 ALDH1A1 (0.71) TSHRALDH1A1GAAPOLBL3MBTL1
SCHEMBL6631517 0.85 ALDH1A1 (0.71) TSHRALDH1A1GAAPOLBL3MBTL1
SCHEMBL22556257 0.78 ALDH1A1 (0.47) TSHRALDH1A1GAAPOLBL3MBTL1
SCHEMBL11619724 0.77 ALDH1A1 (0.69) TSHRALDH1A1GAAPOLBL3MBTL1
SCHEMBL22570460 0.77 ALDH1A1 (0.69) TSHRALDH1A1GAAPOLBL3MBTL1
SCHEMBL6988590 0.74 ALDH1A1 (0.50) ALDH1A1GAAPOLBL3MBTL1CYP2D6
SCHEMBL8256096 0.73 TSHR (1.00) TSHRALDH1A1CYP3A4CYP2D6HPGD
SCHEMBL6999724 0.73 ALDH1A1 (0.49) ALDH1A1GAAPOLBL3MBTL1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019135600-A1 NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME 기초과학연구원 2019-07-11 WO disclosed