Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13637139 | 0.68 | NPSR1 (0.33) | NPSR1 | |
| SCHEMBL761687 | 0.68 | MEN1 (0.39) | ALDH1A1HTR1ADRD2HTR2A | |
| SCHEMBL23023810 | 0.64 | ALDH1A1 (0.33) | ALDH1A1PLA2G7 | |
| SCHEMBL1708741 | 0.64 | — | — | |
| SCHEMBL6195706 | 0.64 | — | — | |
| SCHEMBL14088646 | 0.61 | SOS1 (0.39) | — | |
| SCHEMBL26755919 | 0.60 | BRD4 (0.38) | — | |
| SCHEMBL20417900 | 0.60 | CHRM2 (0.32) | NPSR1 | |
| SCHEMBL20417912 | 0.60 | CRBN (0.42) | — | |
| SCHEMBL12944443 | 0.60 | DRD4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136442-A1 | CD16A BINDING AGENTS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |