Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.47 |
| ▸ | F10 | P00742 | 3/20 | 0.46 |
| ▸ | HPN | P05981 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 5/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | DRD4 | P21917 | 4/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11390291 | 0.87 | CHRM2 (0.60) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL2855094 | 0.82 | TP53 (0.59) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL21151769 | 0.80 | CYP2D6 (0.51) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL1307073 | 0.75 | MEN1 (0.53) | KMT2AF10PRSS1F2 | |
| SCHEMBL27524721 | 0.75 | RECQL (0.60) | DRD3DRD2DRD4 | |
| SCHEMBL29450073 | 0.75 | KMT2A (0.76) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL16416392 | 0.75 | KMT2A (0.76) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL21150819 | 0.74 | TP53 (0.67) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL11139482 | 0.74 | KMT2A (0.57) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL1134938 | 0.73 | SIGMAR1 (0.72) | POLBKMT2ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136442-A1 | CD16A BINDING AGENTS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |