Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 2/20 | 0.43 |
| ▸ | BIRC3 | Q13489 | 2/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2622154 | 1.00 | ALDH1A1 (0.44) | ALDH1A1CYP2D6SMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL17554688 | 0.87 | XIAP (0.48) | ALDH1A1CYP2D6SMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL17554687 | 0.86 | XIAP (0.48) | ALDH1A1CYP2D6SMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL2631840 | 0.85 | XIAP (0.63) | XIAPBIRC3 | |
| SCHEMBL2115252 | 0.85 | XIAP (0.63) | XIAPBIRC3 | |
| SCHEMBL2113962 | 0.84 | XIAP (0.46) | ALDH1A1CYP2D6SMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL2622153 | 0.84 | XIAP (0.46) | ALDH1A1CYP2D6SMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL2622156 | 0.78 | XIAP (0.45) | ALDH1A1XIAPBIRC3HTT | |
| SCHEMBL2117977 | 0.78 | XIAP (0.45) | ALDH1A1XIAPBIRC3HTT | |
| SCHEMBL2632146 | 0.77 | XIAP (0.65) | XIAPBIRC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120094917-A1 | IAP INHIBITORS | TETRALOGIC PHARMACEUTICALS CORP (US) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094917-A1 | IAP INHIBITORS | XIAP, IAPP, BIRC5 | ALDH1A1 4750/4885CYP2D6 4319/4885SMN1; SMN2 1032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.