Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 3/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20160133 | 0.86 | TOP2A (0.49) | TOP2ATOP2BKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL25884924 | 0.83 | TOP2A (0.47) | TOP2ATOP2BKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL25884564 | 0.83 | TOP2A (0.47) | TOP2ATOP2BKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13632263 | 0.82 | GAA (0.55) | TOP2ATOP2BKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL25829161 | 0.82 | KMT2A (0.59) | KMT2AMEN1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL452919 | 0.82 | MEN1 (0.55) | TOP2ATOP2BKMT2AMEN1ALDH1A1 | |
| SCHEMBL19513381 | 0.81 | MEN1 (0.58) | TOP2ATOP2BKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL12898184 | 0.80 | NAAA (0.54) | TOP2ATOP2BMAPTALDH1A1RAB9A | |
| SCHEMBL18232048 | 0.80 | NAAA (0.54) | TOP2ATOP2BKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1936309 | 0.80 | TOP2A (0.50) | TOP2ATOP2BKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11254705-B2 | Cyclic peptide analogs and conjugates thereof | SIRENAS LLC (US) | 2022-02-22 | — | — | US | disclosed |
| US-20190211060-A1 | CYCLIC PEPTIDE ANALOGS AND CONJUGATES THEREOF | SIRENAS LLC (US) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190211060-A1 | CYCLIC PEPTIDE ANALOGS AND CONJUGATES THEREOF | VIP, NGLY1, GRPR | TOP2A 539/4885TOP2B 562/4885KMT2A 4259/4885 |
| US-11254705-B2 | Cyclic peptide analogs and conjugates thereof | VIP, NGLY1, GRPR | TOP2A 539/4885TOP2B 562/4885KMT2A 4259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.