SCHEMBL21152655

SCHEMBL21152655

CCCC1O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@]2(C(=O)COC(=O)N(CC)CCNCC)O1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 P04150 14/20 0.57
▸ HIF1A Q16665 3/20 0.57
▸ LMNA P02545 3/20 0.57
▸ PGR P06401 3/20 0.57
▸ AR P10275 2/20 0.57
▸ ALDH1A1 P00352 1/20 0.57
▸ MEN1 O00255 1/20 0.57
▸ KMT2A Q03164 1/20 0.57
▸ CYP3A4 P08684 1/20 0.52
▸ MAPT P10636 1/20 0.52
▸ HSD17B10 Q99714 1/20 0.52
▸ TDP1 Q9NUW8 1/20 0.52
▸ KDM4E B2RXH2 1/20 0.52
▸ MAPK1 P28482 1/20 0.52
▸ ESR1 P03372 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21153730 0.92 NR3C1 (0.59) NR3C1HIF1ALMNAPGRAR
SCHEMBL21153568 0.90 NR3C1 (0.57) NR3C1HIF1ALMNAPGRAR
SCHEMBL21152549 0.88 NR3C1 (0.58) NR3C1HIF1ALMNAPGRAR
SCHEMBL7740474 0.86 NR3C1 (0.75) NR3C1HIF1ALMNAPGRAR
SCHEMBL21153166 0.86 NR3C1 (0.66) NR3C1HIF1ALMNAPGRAR
SCHEMBL21152782 0.86 NR3C1 (0.60) NR3C1HIF1ALMNAPGRAR
SCHEMBL21152867 0.86 NR3C1 (0.60) NR3C1HIF1ALMNAPGRAR
SCHEMBL24923460 0.86 NR3C1 (0.61) NR3C1HIF1ALMNAPGRAR
SCHEMBL21569798 0.86 NR3C1 (0.61) NR3C1HIF1ALMNAPGRAR
SCHEMBL21153731 0.85 NR3C1 (0.58) NR3C1HIF1ALMNAPGRAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497460-B2 Anti-MSR1 antibodies and methods of use thereof REGENERON PHARMACEUTICALS, INC. (US) 2025-12-16 — — US disclosed
US-20250064954-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2025-02-27 — — US disclosed
US-20240342299-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMA (US) 2024-10-17 — — US disclosed
US-12070506-B2 Steroids and antibody-conjugates thereof REGENERON PHARMACEUTICALS, INC. (US) 2024-08-27 — — US disclosed
US-20230079407-A1 ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF REGENERON PHARMACEUTICALS, INC. 2023-03-16 — — US disclosed
US-11377502-B2 Anti-MSR1 antibodies and methods of use thereof REGENERON PHARMACEUTICALS, INC. (US) 2022-07-05 — — US disclosed
US-11377502-B2 Anti-MSR1 antibodies and methods of use thereof REGENERON PHARMACEUTICALS, INC. (US) 2022-07-05 — — US disclosed
WO-2019217591-A1 ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2019-11-14 — — WO disclosed
US-20190209702-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2019-07-11 — — US disclosed
WO-2019136487-A2 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2019-07-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190209702-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 NR3C1 2/4885HIF1A 3323/4885LMNA 4156/4885
US-20240342299-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 NR3C1 2/4885HIF1A 3323/4885LMNA 4156/4885
US-12070506-B2 Steroids and antibody-conjugates thereof SERPINA6, NR3C1, NR3C2 NR3C1 2/4885HIF1A 3323/4885LMNA 4156/4885
US-20230079407-A1 ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF CD47, MSR1, LDLR NR3C1 1628/4885HIF1A 2218/4885LMNA 2924/4885
US-20250064954-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 NR3C1 2/4885HIF1A 3323/4885LMNA 4156/4885
US-12497460-B2 Anti-MSR1 antibodies and methods of use thereof CD47, MSR1, LDLR NR3C1 1628/4885HIF1A 2218/4885LMNA 2924/4885
US-11377502-B2 Anti-MSR1 antibodies and methods of use thereof CD47, MSR1, LDLR NR3C1 1628/4885HIF1A 2218/4885LMNA 2924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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