Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 11/20 | 0.33 |
| ▸ | MMP3 | P08254 | 9/20 | 0.33 |
| ▸ | MMP9 | P14780 | 8/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21153258 | 0.88 | ACE (0.36) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL21153259 | 0.86 | BMP1 (0.37) | BMP1MMP1MMP3MMP9ACE | |
| SCHEMBL21153877 | 0.84 | BMP1 (0.36) | BMP1MMP1MMP3MMP9ACE | |
| SCHEMBL21153327 | 0.84 | BMP1 (0.34) | BMP1MMP1MMP3ACEKDM4E | |
| SCHEMBL21153850 | 0.79 | BMP1 (0.32) | BMP1 | |
| SCHEMBL19934722 | 0.77 | — | — | |
| SCHEMBL21153326 | 0.76 | BMP1 (0.37) | BMP1MMP1MMP3MMP9ACE | |
| SCHEMBL21153875 | 0.76 | BMP1 (0.39) | BMP1MMP1MMP3MMP9ACE | |
| SCHEMBL19934718 | 0.71 | — | — | |
| SCHEMBL4990551 | 0.70 | BMP1 (0.45) | BMP1MMP1MMP3MMP9ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508476-A1 | AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION | Inst Of Radiation Medicine Chinese Acad Of Medical Sciences (CN) | 2019-07-10 | — | — | EP | disclosed |