SCHEMBL21153348

SCHEMBL21153348

CCNCC(CS)NCCNCC(CS)NCC

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.31
CNR1 P21554 1/20 0.31
ADRA1A P35348 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ABCC3 O15438 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21153304 0.92 LMNA (0.33) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL21153276 0.92 CYP2C19 (0.33)
SCHEMBL21153085 0.85 KDM4E (0.31) KDM4E
SCHEMBL21134882 0.85 KDM4E (0.31) KDM4E
SCHEMBL21135006 0.85 KDM4E (0.31) KDM4E
SCHEMBL21134699 0.85 KDM4E (0.31) KDM4E
SCHEMBL21153031 0.85 KDM4E (0.31) KDM4E
SCHEMBL21135256 0.85 KDM4E (0.31) KDM4E
SCHEMBL21134690 0.85 KDM4E (0.31) KDM4E
SCHEMBL19934648 0.85 KDM4E (0.31) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3508476-B1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION SHANGHAI KECHOW PHARMA INC (CN) 2023-11-22 EP disclosed
EP-3508476-A1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION Inst Of Radiation Medicine Chinese Acad Of Medical Sciences (CN) 2019-07-10 EP disclosed