Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 3/20 | 0.42 |
| ▸ | KIF11 | P52732 | 9/20 | 0.42 |
| ▸ | SUCNR1 | Q9BXA5 | 4/20 | 0.40 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21153574 | 0.85 | KIF11 (0.45) | MPLKIF11SUCNR1TRPV3FFAR1 | |
| SCHEMBL22766122 | 0.83 | KIF11 (0.42) | MPLKIF11SUCNR1TRPV3FFAR1 | |
| SCHEMBL31030963 | 0.81 | MPL (0.55) | MPLKIF11PDE3BPDE3AKMO | |
| SCHEMBL26266155 | 0.79 | SUCNR1 (0.40) | MPLKIF11SUCNR1TRPV3FFAR1 | |
| SCHEMBL13906328 | 0.78 | AR (0.59) | MPLKIF11PDE3BPDE3AKMO | |
| SCHEMBL1104680 | 0.76 | SLC6A4 (0.42) | MPLKIF11 | |
| SCHEMBL12603794 | 0.74 | KIF11 (0.51) | MPLKIF11SUCNR1PDE3BPDE3A | |
| SCHEMBL22064887 | 0.73 | SLC6A4 (0.40) | MPLTRPV3 | |
| SCHEMBL13906292 | 0.73 | MPL (0.49) | MPLKIF11PDE3BPDE3AKMO | |
| SCHEMBL2399327 | 0.73 | PDE2A (0.43) | MPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183776-A2 | TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION | NEW YORK UNIVERSITY (US) | 2023-09-28 | — | — | WO | disclosed |
| WO-2019136022-A1 | PERIODONTAL DISEASE THERAPY | NEW YORK UNIVERSITY (US) | 2019-07-11 | — | — | WO | disclosed |