SCHEMBL21153941

SCHEMBL21153941

N=C(/N=C(\Nn1c2ccccc2c2cc(-c3ccc4c(c3)c3ccccc3n4-c3ccccc3)ccc21)c1ccc2c3ccccc3c3ccccc3c2c1)c1ccc2c3ccccc3c3ccccc3c2c1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PTGER4 P35408 1/20 0.34
HDAC4 P56524 1/20 0.31
F2 P00734 1/20 0.30
F10 P00742 1/20 0.30
PRSS1 P07477 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21154295 0.93 KDM4E (0.31) KDM4EATML3MBTL1PTGER4
SCHEMBL21153900 0.89 L3MBTL1 (0.40) KDM4EATML3MBTL1PTGER4HDAC4
SCHEMBL21154296 0.89 KDM4E (0.32) KDM4EATML3MBTL1
SCHEMBL21153946 0.89 KDM4E (0.32) KDM4EATML3MBTL1
SCHEMBL21154286 0.88 KDM4E (0.31) KDM4EATML3MBTL1HDAC4
SCHEMBL21153897 0.87 KDM4E (0.38) KDM4EATML3MBTL1PTGER4HDAC4
SCHEMBL21154356 0.86 KDM4E (0.32) KDM4EATML3MBTL1PTGER4
SCHEMBL21153895 0.85 L3MBTL1 (0.36) KDM4EATML3MBTL1PTGER4HDAC4
SCHEMBL21153953 0.84 KDM4E (0.32) KDM4EATML3MBTL1PRSS1
SCHEMBL21153951 0.84 NR4A2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2674418-B1 BISCARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO (JP) 2021-01-06 EP disclosed
EP-2568030-B1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING SAME, AND DISPLAY DEVICE INCLUDING ORGANIC LIGHT EMITTING DIODE CHEIL IND INC (KR) 2019-12-25 EP disclosed
EP-3514846-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING SAME, AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE Cheil Industries Inc. (KR) 2019-07-24 EP disclosed
EP-3509121-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING SAME, AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE Cheil Industries Inc. (KR) 2019-07-10 EP disclosed