⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12899543 | 0.79 | — | — | |
| SCHEMBL12928811 | 0.79 | — | — | |
| SCHEMBL12222439 | 0.75 | — | — | |
| SCHEMBL13384019 | 0.75 | — | — | |
| SCHEMBL14049564 | 0.75 | — | — | |
| SCHEMBL21264908 | 0.74 | — | — | |
| SCHEMBL12999734 | 0.71 | — | — | |
| SCHEMBL22800140 | 0.71 | — | — | |
| SCHEMBL5177639 | 0.71 | — | — | |
| SCHEMBL12222435 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136157-A2 | REDUCING BETA-CATENIN AND IDO EXPRESSION TO POTENTIATE IMMUNOTHERAPY | DICERNA PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |