Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19321820 | 0.67 | CRBN (0.32) | SMN1; SMN2 | |
| SCHEMBL165377 | 0.67 | — | — | |
| SCHEMBL11020381 | 0.65 | — | — | |
| SCHEMBL9095232 | 0.65 | — | — | |
| SCHEMBL22100208 | 0.64 | SMN1; SMN2 (0.37) | SMN1; SMN2 | |
| SCHEMBL27592051 | 0.64 | — | — | |
| SCHEMBL1705413 | 0.63 | — | — | |
| SCHEMBL12580876 | 0.62 | LMNA (0.41) | TSHR | |
| SCHEMBL13559260 | 0.62 | LMNA (0.41) | TSHR | |
| SCHEMBL13559217 | 0.62 | LMNA (0.41) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793590-B2 | Antifungal compounds | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-10-06 | — | — | US | disclosed |
| US-20190211047-A1 | ANTIFUNGAL COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10793590-B2 | Antifungal compounds | DPM1, NACA, SUCLG1 | SMN1; SMN2 2190/4885TSHR 4480/4885 |
| US-20190211047-A1 | ANTIFUNGAL COMPOUNDS | DPM1, NACA, SUCLG1 | SMN1; SMN2 2190/4885TSHR 4480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.