SCHEMBL21154945

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18682743	0.90	AR (0.54)	ARGABRPGABRDNR1I2NR3C1
	SCHEMBL20003379	0.82	AR (0.53)	ARGABRPGABRDNR1I2NR3C1
	SCHEMBL20003273	0.81	AR (0.62)	ARGABRPGABRDNR1I2NR3C1
	SCHEMBL10155477	0.81	AR (0.53)	ARGABRPGABRDNR1I2NR3C1
	SCHEMBL14389844	0.81	AR (0.53)	ARGABRPGABRDNR1I2NR3C1
	SCHEMBL18682744	0.79	AR (0.53)	ARNR3C1
	SCHEMBL1715855	0.77	AR (0.53)	ARGABRPGABRDNR1I2NR3C1
	SCHEMBL1715853	0.77	AR (0.53)	ARGABRPGABRDNR1I2NR3C1
	SCHEMBL29508757	0.77	AR (0.53)	ARGABRPGABRDNR1I2NR3C1
	SCHEMBL20003389	0.77	AR (0.55)	ARGABRPGABRDNR1I2NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.