Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2622113 | 1.00 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2KCNQ3KCNQ2XIAP | |
| SCHEMBL2632168 | 0.86 | XIAP (0.58) | XIAPBIRC3 | |
| SCHEMBL2115200 | 0.86 | XIAP (0.58) | XIAPBIRC3 | |
| SCHEMBL2632238 | 0.86 | XIAP (0.58) | XIAPBIRC3 | |
| SCHEMBL17577899 | 0.85 | XIAP (0.42) | ALDH1A1SMN1; SMN2KCNQ3KCNQ2XIAP | |
| SCHEMBL2117361 | 0.85 | XIAP (0.42) | ALDH1A1SMN1; SMN2KCNQ3KCNQ2XIAP | |
| SCHEMBL2622112 | 0.85 | XIAP (0.42) | ALDH1A1SMN1; SMN2KCNQ3KCNQ2XIAP | |
| SCHEMBL2733398 | 0.81 | DPP4 (0.43) | DPP8DPP4DPP9DPP7 | |
| SCHEMBL10284304 | 0.79 | XIAP (0.51) | XIAPBIRC3 | |
| SCHEMBL2115932 | 0.79 | XIAP (0.51) | XIAPBIRC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120094917-A1 | IAP INHIBITORS | TETRALOGIC PHARMACEUTICALS CORP (US) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094917-A1 | IAP INHIBITORS | XIAP, IAPP, BIRC5 | ALDH1A1 4750/4885SMN1; SMN2 1032/4885KCNQ3 4396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.