Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | CNR2 | P34972 | 10/20 | 0.52 |
| ▸ | CNR1 | P21554 | 9/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21154852 | 1.00 | CYP1A2 (0.66) | CYP1A2CYP3A4CYP2D6CYP2C9TSHR | |
| SCHEMBL21154835 | 1.00 | CYP1A2 (0.66) | CYP1A2CYP3A4CYP2D6CYP2C9TSHR | |
| SCHEMBL21154890 | 0.97 | CYP1A2 (0.67) | CYP1A2CYP3A4CYP2D6CYP2C9TSHR | |
| SCHEMBL24468087 | 0.91 | TSHR (0.67) | CYP1A2CYP3A4CYP2D6CYP2C9TSHR | |
| SCHEMBL24468058 | 0.90 | CYP1A2 (0.66) | CYP1A2CYP3A4CYP2D6CYP2C9TSHR | |
| SCHEMBL14595147 | 0.89 | CYP1A2 (0.72) | CYP1A2CYP3A4CYP2D6CYP2C9TSHR | |
| SCHEMBL14584137 | 0.88 | TSHR (0.71) | CYP1A2CYP3A4CYP2D6CYP2C9TSHR | |
| SCHEMBL21155363 | 0.87 | CYP1A2 (0.61) | CYP1A2CYP3A4CYP2D6CYP2C9TSHR | |
| SCHEMBL24486720 | 0.84 | CYP1A2 (0.75) | CYP1A2CYP3A4CYP2D6CYP2C9TSHR | |
| SCHEMBL996941 | 0.83 | CYP1A2 (0.77) | CYP1A2CYP3A4CYP2D6CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136154-A1 | MITO-LONIDAMINE, COMPOSITIONS AND METHODS OF USE | THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) | 2019-07-11 | — | — | WO | disclosed |