Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 4/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118555 | 0.86 | PAK1 (0.48) | PAK1ALDH1A1HPGDTP53HSD17B10 | |
| SCHEMBL1725582 | 0.82 | PAK1 (0.62) | PAK1ALDH1A1HPGDTP53HSD17B10 | |
| SCHEMBL10927535 | 0.81 | PAK1 (0.61) | PAK1ALDH1A1HPGDMAPTHTT | |
| SCHEMBL8826229 | 0.81 | PAK1 (0.61) | PAK1ALDH1A1HPGDMAPTHTT | |
| SCHEMBL10925300 | 0.81 | PAK1 (0.61) | PAK1ALDH1A1HPGDMAPTHTT | |
| SCHEMBL240979 | 0.79 | TP53 (0.52) | PAK1ALDH1A1TP53HSD17B10NOTUM | |
| SCHEMBL11476556 | 0.79 | PAK1 (0.38) | PAK1ALDH1A1TSHRCDC7DBF4 | |
| SCHEMBL2888984 | 0.79 | G6PD (0.48) | PAK1ALDH1A1HPGDTP53HSD17B10 | |
| SCHEMBL10426488 | 0.78 | SMN1; SMN2 (0.41) | PAK1ALDH1A1TP53HSD17B10NOTUM | |
| SCHEMBL29951296 | 0.78 | NOTUM (0.36) | PAK1ALDH1A1HPGDTP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2711009-A1 | Compounds for use in treating or preventing primary and metastatic breast and prostate cancer | Institut Univ. de Ciència i Tecnologia, S.A. (ES) | 2014-03-26 | — | — | EP | claimed |
| EP-2711008-A1 | N6,N6-dimethyladenosine for use in treating or preventing primary and metastatic breast cancer | Institut Univ. de Ciència i Tecnologia, S.A. (ES) | 2014-03-26 | — | — | EP | claimed |
| EP-2711007-A1 | 4-Aminopyrazolo[3,4-d]pyrimidine for use in treating or preventing primary and metastatic breast and prostate cancer | Institut Univ. de Ciència i Tecnologia, S.A. (ES) | 2014-03-26 | — | — | EP | claimed |
| CN-118772218-A | Preparation method of alkyl thioether purine/alkyl thioether purine nucleoside | 东南大学 | 2024-10-15 | — | — | CN | disclosed |
| US-20150119351-A1 | THERAPY OF TUMORS AND INFECTIOUS AGENTS DEFICIENT IN METHYLTHIOADENOSINE PHOSPHORYLASE | LUBIN ADAM (US) | 2015-04-30 | — | — | US | disclosed |
| US-8796241-B2 | Therapy of tumors and infectious agents deficient in methylthioadenosine phosphorylase | LUBIN ADAM (US) | 2014-08-05 | — | — | US | disclosed |
| EP-2711007-A1 | 4-Aminopyrazolo[3,4-d]pyrimidine for use in treating or preventing primary and metastatic breast and prostate cancer | Institut Univ. de Ciència i Tecnologia, S.A. (ES) | 2014-03-26 | — | — | EP | disclosed |
| EP-2711008-A1 | N6,N6-dimethyladenosine for use in treating or preventing primary and metastatic breast cancer | Institut Univ. de Ciència i Tecnologia, S.A. (ES) | 2014-03-26 | — | — | EP | disclosed |
| EP-2711009-A1 | Compounds for use in treating or preventing primary and metastatic breast and prostate cancer | Institut Univ. de Ciència i Tecnologia, S.A. (ES) | 2014-03-26 | — | — | EP | disclosed |
| US-20120094947-A1 | METHOD FOR THE SELECTIVE THERAPY OF DISEASE | LUBIN ADAM (US) | 2012-04-19 | — | — | US | disclosed |
| EP-2192905-A2 | METHOD FOR THE SELECTIVE THERAPY OF DISEASE | Lubin, Adam (US) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009032057-A2 | METHOD FOR THE SELECTIVE THERAPY OF DISEASE | LUBIN ADAM (US) | 2009-03-12 | — | — | WO | disclosed |
| US-7312022-B2 | Developing solution contains a heterocyclic compound having three or more heteroatoms which when added, capable of enhancing the sensitivity of the silver halide color photosensitive material; high sensitivity, excellent color image storability | FUJIFILM CORPORATION (JP) | 2007-12-25 | — | — | US | disclosed |
| US-7312022-B2 | Developing solution contains a heterocyclic compound having three or more heteroatoms which when added, capable of enhancing the sensitivity of the silver halide color photosensitive material; high sensitivity, excellent color image storability | FUJIFILM CORPORATION (JP) | 2007-12-25 | — | — | US | disclosed |
| EP-0286425-B1 | Therapeutic nucleosides | WELLCOME FOUND (GB) | 1995-01-11 | — | — | EP | disclosed |
| US-5185437-A | 6-substituted 2',3'-dideoxypurine nucleosides; treatment for human immunodeficiency virus and heptatis b virus | BURROUGHS WELLCOME CO. (US) | 1993-02-09 | — | — | US | disclosed |
| US-5068320-A | 2-amino-6-(cyclopropylamino)purine-9-β-D-2',3'-dideoxyribofuranoside and its pharmaceutically acceptable salts | BURROUGHS WELLCOME CO. (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0421819-A1 | Therapeutic nucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-04-10 | — | — | EP | disclosed |
| EP-0286425-A2 | Therapeutic nucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-10-12 | — | — | EP | disclosed |